Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.59 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.59 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.56 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1733385 | 0.91 | KDM4E (0.67) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7480760 | 0.86 | LMNA (0.63) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7479676 | 0.80 | KDM4E (0.65) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL1732832 | 0.78 | KDM4E (0.62) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7482289 | 0.77 | KDM4E (0.65) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL14907131 | 0.77 | KDM4E (0.81) | ALDH1A1KDM4EHSD17B10HPGDNPSR1 | |
| SCHEMBL4098536 | 0.77 | CHEK1 (0.84) | LMNAALDH1A1HPGDNPSR1RAB9A | |
| SCHEMBL1732688 | 0.76 | MAPT (0.68) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL1732689 | 0.76 | MAPT (0.68) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7478023 | 0.76 | KDM4E (0.63) | LMNAALDH1A1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229010-A1 | NOVEL DIARYLAMIDE DERIVATIVES AND USE THEREOF AS MEDICINES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |