SCHEMBL17327893

SCHEMBL17327893

C=CC(=O)Nc1ccc(Oc2ccc(S(=O)(=O)c3ccc(Oc4ccc(NC(=O)C=C)cc4)cc3)cc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 15/20 0.69
F13A1 P00488 7/20 0.57
TGM1 P22735 7/20 0.57
LMNA P02545 1/20 0.51
TGM3 Q08188 1/20 0.51
ALDH1A1 P00352 2/20 0.51
POLB P06746 1/20 0.51
MAPT P10636 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
MAP2K7 O14733 1/20 0.49
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA9 Q16790 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14341775 0.88 TGM2 (0.86) TGM2F13A1TGM1LMNATGM3
SCHEMBL3190721 0.85 TGM2 (0.56) TGM2F13A1TGM1LMNATGM3
SCHEMBL3188863 0.84 TGM2 (0.55) TGM2F13A1TGM1LMNATGM3
SCHEMBL3194158 0.84 TGM2 (0.55) TGM2F13A1TGM1LMNATGM3
SCHEMBL7894169 0.84 TGM2 (0.66) TGM2F13A1TGM1LMNATGM3
SCHEMBL964754 0.83 TGM2 (0.64) TGM2F13A1TGM1LMNATGM3
SCHEMBL19457348 0.83 TGM2 (0.77) TGM2F13A1TGM1LMNATGM3
SCHEMBL9017578 0.82 TGM2 (1.00) TGM2F13A1TGM1LMNATGM3
SCHEMBL22658792 0.82 ALDH1A1 (0.79) TGM2LMNAALDH1A1POLBMAPT
SCHEMBL20456243 0.81 TGM2 (0.73) TGM2F13A1TGM1LMNATGM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170333846-A1 COMPOSITE ANION EXCHANGE MEMBRANE, METHOD FOR PRODUCING THE SAME, ION EXCHANGE MEMBRANE MODULE, AND ION EXCHANGE DEVICE FUJIFILM CORPORATION (JP) 2017-11-23 US disclosed
US-20160177006-A1 ION EXCHANGE FILM, COMPOSITION FOR FORMING ION EXCHANGE FILM, AND PRODUCTION METHOD FOR ION EXCHANGE FILM FUJIFILM CORPORATION (JP) 2016-06-23 US disclosed
EP-2965803-A1 FUNCTIONAL POLYMER MEMBRANE, MANUFACTURING METHOD THEREFOR, ION EXCHANGE MEMBRANE AND PROTON CONDUCTING MEMBRANE EQUIPPED WITH FUNCTIONAL POLYMER MEMBRANE, AND ION EXCHANGE DEVICE FUJIFILM Corporation (JP) 2016-01-13 EP disclosed
US-20150353696-A1 FUNCTIONAL POLYMER MEMBRANE, MANUFACTURING METHOD THEREFOR, ION EXCHANGE MEMBRANE AND PROTON CONDUCTIVE MEMBRANE EQUIPPED WITH FUNCTIONAL POLYMER MEMBRANE, AND ION EXCHANGE DEVICE FUJIFILM CORPORATION (JP) 2015-12-10 US disclosed