Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 11/20 | 0.77 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | F13A1 | P00488 | 5/20 | 0.58 |
| ▸ | TGM1 | P22735 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.51 |
| ▸ | NMT1 | P30419 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL648950 | 0.88 | TGM2 (1.00) | TGM2F13A1TGM1ALDH1A1LMNA | |
| SCHEMBL3821674 | 0.86 | ALDH1A1 (0.71) | TGM2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9568792 | 0.86 | ALDH1A1 (0.71) | TGM2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL19457358 | 0.86 | NAMPT (0.61) | TGM2PKMF13A1TGM1MEN1 | |
| SCHEMBL19457350 | 0.86 | TGM2 (0.56) | TGM2PKMF13A1TGM1MEN1 | |
| SCHEMBL7894169 | 0.85 | TGM2 (0.66) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL964754 | 0.84 | TGM2 (0.64) | TGM2PKMF13A1TGM1LMNA | |
| SCHEMBL20885056 | 0.83 | TGM2 (0.63) | TGM2PKMF13A1TGM1ALDH1A1 | |
| SCHEMBL8465028 | 0.83 | TGM2 (0.89) | TGM2F13A1TGM1ALDH1A1LMNA | |
| SCHEMBL17327893 | 0.83 | TGM2 (0.69) | TGM2F13A1TGM1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3440084-B1 | PYRIMIDO-DIAZEPINONE KINASE SCAFFOLD COMPOUNDS AND METHODS OF TREATING PI3K-MEDIATED DISORDERS | DANA FARBER CANCER INST INC (US) | 2022-12-21 | — | — | EP | disclosed |
| WO-2017177092-A1 | PYRIMIDO-DIAZEPINONE KINASE SCAFFOLD COMPOUNDS AND METHODS OF TREATING PI3K-MEDIATED DISORDERS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-10-12 | — | — | WO | disclosed |
| CN-102256792-B | Radiation-sensitive compositions and elements containing poly(vinyl hydroxyaryl carboxylic acid ester)s | EASTMAN KODAK CO | 2014-08-20 | — | — | CN | disclosed |
| CN-102256792-A | Radiation-sensitive compositions and elements containing poly(vinyl hydroxyaryl carboxylic acid ester)s | EASTMAN KODAK CO | 2011-11-23 | — | — | CN | disclosed |