SCHEMBL173368

SCHEMBL173368

Cc1ccccc1-c1cc(N)ccc1N

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G7 Q13093 1/20 0.56
CASP1 P29466 2/20 0.46
NPC1 O15118 5/20 0.46
RAB9A P51151 4/20 0.46
SMN1; SMN2 Q16637 4/20 0.46
TSHR P16473 3/20 0.46
KDM4E B2RXH2 3/20 0.46
TP53 P04637 2/20 0.46
MAPT P10636 2/20 0.46
HSD17B10 Q99714 2/20 0.46
ALDH1A1 P00352 5/20 0.45
CYP3A4 P08684 3/20 0.45
TDP1 Q9NUW8 2/20 0.45
MAPK1 P28482 1/20 0.45
PTPRC P08575 2/20 0.44
LMNA P02545 2/20 0.44
HPGD P15428 2/20 0.44
MEN1 O00255 1/20 0.44
APAF1 O14727 1/20 0.44
TDP2 O95551 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6570879 0.98 PLA2G7 (0.55) PLA2G7CASP1NPC1RAB9ASMN1; SMN2
SCHEMBL10094651 0.87 PLA2G7 (0.71) PLA2G7CASP1NPC1RAB9ASMN1; SMN2
SCHEMBL4229761 0.85 PTPRC (0.61) PLA2G7CASP1NPC1RAB9ASMN1; SMN2
SCHEMBL3953592 0.85 CYP3A4 (0.45) PLA2G7CASP1NPC1RAB9ASMN1; SMN2
SCHEMBL6011421 0.83 CASP1 (0.52) PLA2G7CASP1NPC1RAB9ASMN1; SMN2
SCHEMBL3780745 0.83 PLA2G7 (0.67) PLA2G7CASP1NPC1RAB9ASMN1; SMN2
SCHEMBL1461185 0.83 PLA2G7 (0.55) PLA2G7CASP1NPC1RAB9ASMN1; SMN2
Hydrochloric Acid SCHEMBL6574527 0.82 PLA2G7 (0.43) PLA2G7CASP1NPC1RAB9ASMN1; SMN2
SCHEMBL5133404 0.82 ALDH1A1 (0.65) PLA2G7CASP1NPC1RAB9ASMN1; SMN2
SCHEMBL6933397 0.82 PLA2G7 (0.44) PLA2G7CASP1NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116589761-A Environment-friendly sole material and preparation method thereof 薛天翔 2023-08-15 CN claimed
CN-110734380-B Preparation method of diaryl p-phenylenediamine anti-aging agent 圣奥化学科技有限公司 2023-04-25 CN claimed
CN-109689792-B Liquid antioxidant composition for raw rubber 巴斯夫欧洲公司 2022-03-29 CN claimed
CN-110734380-A preparation method of diaryl p-phenylenediamine anti-aging agent 圣奥化学科技有限公司 2020-01-31 CN claimed
EP-2611797-A2 QUINOLINE OR QUINAZOLINE DERIVATIVES WITH APOPTOSIS INDUCING ACTIVITY ON CELLS Hanmi Science Co., Ltd. (KR) 2013-07-10 EP claimed
WO-2012030160-A2 QUINOLINE OR QUINAZOLINE DERIVATIVES WITH APOPTOSIS INDUCING ACTIVITY ON CELLS HANMI HOLDINGS CO., LTD. (KR) 2012-03-08 WO claimed
EP-1051143-B1 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES WELLA AG (DE) 2004-07-21 EP claimed
US-6500213-B1 Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives WELLA AKTIENGESELLSCHAFT (DE) 2002-12-31 US claimed
EP-1051143-A2 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES Wella Aktiengesellschaft (DE) 2000-11-15 EP claimed
WO-1999059527-A2 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES WELLA AKTIENGESELLSCHAFT (DE) 1999-11-25 WO claimed
US-20260015486-A1 RUBBER COMPOSITIONS AND ARTICLES THEREOF GOODYEAR TIRE & RUBBER (US) 2026-01-15 US disclosed
EP-4678693-A1 RUBBER COMPOSITIONS AND ARTICLES THEREOF The Goodyear Tire & Rubber Company (US) 2026-01-14 EP disclosed
CN-118085584-A Tear-resistant fluorosilicone rubber compound and preparation method thereof 温州合丰胶业股份有限公司 2024-05-28 CN disclosed
CN-114207036-B Polyphenylene sulfide/polyamide compositions 巴斯夫欧洲公司 2024-05-24 CN disclosed
CN-116589761-A Environment-friendly sole material and preparation method thereof 薛天翔 2023-08-15 CN disclosed
EP-1935919-A1 POLYMER CONTAINING SULFO GROUP AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THE POLYMER Mitsui Chemicals, Inc. (JP) 2008-06-25 EP disclosed
EP-1051143-B1 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES WELLA AG (DE) 2004-07-21 EP disclosed
US-6500213-B1 Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives WELLA AKTIENGESELLSCHAFT (DE) 2002-12-31 US disclosed
EP-1051143-A2 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES Wella Aktiengesellschaft (DE) 2000-11-15 EP disclosed
WO-1999059527-A2 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES WELLA AKTIENGESELLSCHAFT (DE) 1999-11-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015486-A1 RUBBER COMPOSITIONS AND ARTICLES THEREOF RECQL, TRDMT1, BLM PLA2G7 2007/4885CASP1 1264/4885NPC1 2513/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.