Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | IL1B | P01584 | 3/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | OGFRL1 | Q5TC84 | 3/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | PIK3R2 | O00459 | 2/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17338395 | 0.93 | IL1B (0.43) | IL1BP2RX7PIK3CDOPRM1OGFRL1 | |
| SCHEMBL17338193 | 0.91 | BTK (0.44) | PDE10AIL1BP2RX7PIK3CDOPRM1 | |
| SCHEMBL17338223 | 0.91 | OPRM1 (0.44) | IL1BP2RX7PIK3CDOPRM1OGFRL1 | |
| SCHEMBL17338184 | 0.86 | OPRM1 (0.44) | IL1BP2RX7PIK3CDOPRM1OGFRL1 | |
| SCHEMBL17330844 | 0.82 | PIK3CD (0.45) | IL1BP2RX7PIK3CDOPRM1OGFRL1 | |
| SCHEMBL17330842 | 0.82 | PIK3CD (0.45) | IL1BP2RX7PIK3CDOPRM1OGFRL1 | |
| SCHEMBL17338397 | 0.81 | POLB (0.41) | PDE10APIK3CDSTSPARP1TNKS2 | |
| SCHEMBL17338161 | 0.81 | PIK3CD (0.47) | PIK3CDOPRM1OGFRL1OPRK1OPRD1 | |
| SCHEMBL17338255 | 0.80 | KEAP1 (0.38) | PDE10AIL1BP2RX7OPRM1OGFRL1 | |
| SCHEMBL17262976 | 0.80 | PIK3CD (0.44) | PIK3CDPIK3CAPIK3R2PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154958-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | Gilead Sciences, Inc. (US) | 2017-04-19 | — | — | EP | disclosed |
| WO-2015191752-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2015-12-17 | — | — | WO | disclosed |