Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.65 |
| ▸ | MMP3 | P08254 | 1/20 | 0.61 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.61 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.58 |
| ▸ | PREP | P48147 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | UQCRB | P14927 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22127728 | 1.00 | ESR1 (0.65) | ESR1ESR2MMP3BCL2L1SENP1 | |
| SCHEMBL25617591 | 1.00 | ESR1 (0.65) | ESR1ESR2MMP3BCL2L1SENP1 | |
| SCHEMBL13569204 | 0.98 | MMP3 (0.65) | ESR1ESR2MMP3BCL2L1SENP1 | |
| SCHEMBL13569147 | 0.98 | MMP3 (0.65) | ESR1ESR2MMP3BCL2L1SENP1 | |
| SCHEMBL29825951 | 0.90 | ESR1 (0.56) | ESR1ESR2MMP3BCL2L1SENP1 | |
| SCHEMBL23380136 | 0.89 | LTA4H (0.59) | ESR1ESR2MMP3BCL2L1SENP1 | |
| SCHEMBL28352143 | 0.89 | ESR1 (0.58) | ESR1ESR2MMP3BCL2L1SENP1 | |
| SCHEMBL20160837 | 0.88 | PDE4B (0.52) | ESR1ESR2P2RX7MEN1KMT2A | |
| SCHEMBL13170491 | 0.88 | PDE4B (0.52) | ESR1ESR2P2RX7MEN1KMT2A | |
| SCHEMBL4250744 | 0.88 | PDE4B (0.52) | ESR1ESR2P2RX7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3151919-A1 | CARBON MONOXIDE-RELEASING MOLECULES FOR THERAPEUTIC APPLICATIONS AND METHODS OF MAKING AND USING THEREOF | Georgia State University Research Foundation, Inc. (US) | 2017-04-12 | — | — | EP | claimed |
| WO-2015191616-A1 | CARBON MONOXIDE-RELEASING MOLECULES FOR THERAPEUTIC APPLICATIONS AND METHODS OF MAKING AND USING THEREOF | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2015-12-17 | — | — | WO | claimed |
| EP-3151919-B1 | CARBON MONOXIDE-RELEASING MOLECULES FOR THERAPEUTIC APPLICATIONS AND METHODS OF MAKING AND USING THEREOF | UNIV GEORGIA STATE RES FOUND (US) | 2023-08-30 | — | — | EP | disclosed |
| US-11420994-B2 | Carbon-monoxide-releasing molecules and therapeutic applications thereof | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2022-08-23 | — | — | US | disclosed |
| US-20210221835-A1 | CARBON-MONOXIDE-RELEASING MOLECULES AND THERAPEUTIC APPLICATIONS THEREOF | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2021-07-22 | — | — | US | disclosed |
| US-10751344-B2 | Carbon monoxide-releasing molecules for therapeutic applications and methods for the preparation and use thereof | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2020-08-25 | — | — | US | disclosed |
| US-20190350937-A1 | CARBON MONOXIDE-RELEASING MOLECULES FOR THERAPEUTIC APPLICATIONS AND METHODS FOR THE PREPARATION AND USE THEREOF | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2019-11-21 | — | — | US | disclosed |
| US-10300069-B2 | Carbon monoxide-releasing molecules for therapeutic applications and methods of making and using thereof | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2019-05-28 | — | — | US | disclosed |
| WO-2018093924-A1 | CARBON MONOXIDE-RELEASING MOLECULES AND THERAPEUTIC APPLICATIONS THEREOF | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2018-05-24 | — | — | WO | disclosed |
| US-20170128456-A1 | CARBON MONOXIDE-RELEASING MOLECULES FOR THERAPEUTIC APPLICATIONS AND METHODS OF MAKING AND USING THEREOF | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC, (US) | 2017-05-11 | — | — | US | disclosed |
| US-20170128456-A1 | CARBON MONOXIDE-RELEASING MOLECULES FOR THERAPEUTIC APPLICATIONS AND METHODS OF MAKING AND USING THEREOF | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC, (US) | 2017-05-11 | — | — | US | disclosed |
| US-20170128456-A1 | CARBON MONOXIDE-RELEASING MOLECULES FOR THERAPEUTIC APPLICATIONS AND METHODS OF MAKING AND USING THEREOF | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC, (US) | 2017-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11420994-B2 | Carbon-monoxide-releasing molecules and therapeutic applications thereof | MB, HMOX1, CYC1 | ESR1 893/4885ESR2 1058/4885MMP3 2755/4885 |
| US-20170128456-A1 | CARBON MONOXIDE-RELEASING MOLECULES FOR THERAPEUTIC APPLICATIONS AND METHODS OF MAKING AND USING THEREOF | MB, CYC1, COX15 | ESR1 1642/4885ESR2 1484/4885MMP3 2631/4885 |
| US-20210221835-A1 | CARBON-MONOXIDE-RELEASING MOLECULES AND THERAPEUTIC APPLICATIONS THEREOF | MB, HMOX1, CYC1 | ESR1 893/4885ESR2 1058/4885MMP3 2755/4885 |
| US-10751344-B2 | Carbon monoxide-releasing molecules for therapeutic applications and methods for the preparation and use thereof | MB, CYC1, HMOX1 | ESR1 1226/4885ESR2 1374/4885MMP3 3010/4885 |
| US-10300069-B2 | Carbon monoxide-releasing molecules for therapeutic applications and methods of making and using thereof | MB, CYC1, COX15 | ESR1 1642/4885ESR2 1484/4885MMP3 2631/4885 |
| US-20190350937-A1 | CARBON MONOXIDE-RELEASING MOLECULES FOR THERAPEUTIC APPLICATIONS AND METHODS FOR THE PREPARATION AND USE THEREOF | MB, CYC1, HMOX1 | ESR1 1226/4885ESR2 1374/4885MMP3 3010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.