Sugi Predict

Sugi Predict / Compounds / SCHEMBL17338697

SCHEMBL17338697

SCHEMBL17338697

CCOC(=O)c1csc(CCNC(=O)OC(C)(C)C)n1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ABCB1 P08183 1/20 0.53
▸ KMT2A Q03164 2/20 0.52
▸ RAB9A P51151 8/20 0.51
▸ NPC1 O15118 7/20 0.51
▸ MAPT P10636 6/20 0.47
▸ HSP90AA1 P07900 2/20 0.47
▸ ALDH1A1 P00352 2/20 0.47
▸ MEN1 O00255 1/20 0.47
▸ CYP1A2 P05177 1/20 0.46
▸ CYP2C19 P33261 1/20 0.46
▸ SMN1; SMN2 Q16637 4/20 0.44
▸ GAA P10253 2/20 0.44
▸ POLB P06746 1/20 0.41
▸ PKM P14618 1/20 0.41
▸ NPSR1 Q6W5P4 1/20 0.41
▸ RXFP1 Q9HBX9 1/20 0.41
▸ TDP1 Q9NUW8 1/20 0.41
▸ HDAC3 O15379 3/20 0.41
▸ HDAC1 Q13547 3/20 0.41
▸ HDAC6 Q9UBN7 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18764846 0.93 ABCB1 (0.51) ABCB1KMT2ARAB9ANPC1MAPT
SCHEMBL18764665 0.89 HDAC3 (0.42) ABCB1KMT2ARAB9ANPC1MAPT
SCHEMBL12830653 0.88 ABCB1 (0.51) ABCB1KMT2ARAB9ANPC1MAPT
SCHEMBL7145374 0.88 ABCB1 (0.54) ABCB1KMT2ARAB9ANPC1MAPT
SCHEMBL18764773 0.85 HDAC3 (0.43) KMT2AALDH1A1MEN1GAANPSR1
SCHEMBL7376437 0.85 ABCB1 (0.52) ABCB1KMT2ARAB9ANPC1MAPT
SCHEMBL14845194 0.83 HDAC3 (0.46) ABCB1KMT2AALDH1A1CYP1A2CYP2C19
SCHEMBL8056593 0.83 ABCB1 (0.50) ABCB1KMT2ARAB9ANPC1MAPT
SCHEMBL4696490 0.82 HTT (0.43) KMT2ARAB9ANPC1MAPTHSP90AA1
SCHEMBL18764790 0.81 ABCB1 (0.53) ABCB1KMT2ARAB9ANPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3364967-B1 FERROPORTIN INHIBITORS VIFOR INT AG (CH) 2026-05-20 — — EP disclosed
EP-3365339-B1 NOVEL FERROPORTIN INHIBITORS VIFOR INT AG (CH) 2025-07-16 — — EP disclosed
US-20220363675-A1 Novel Ferroportin Inhibitors VIFOR (INTERNATIONAL) AG (CH) 2022-11-17 — — US disclosed
CN-114668761-A Novel ferroportin inhibitors 威佛（国际）股份公司 2022-06-28 — — CN disclosed
CN-108290878-B Novel ferroportin inhibitors 威佛（国际）股份公司 2022-04-26 — — CN disclosed
US-11066399-B2 Ferroportin inhibitors VIFOR (INTERNATIONAL) AG (CH) 2021-07-20 — — US disclosed
US-11066399-B2 Ferroportin inhibitors VIFOR (INTERNATIONAL) AG (CH) 2021-07-20 — — US disclosed
US-20210139472-A1 Novel Ferroportin Inhibitors VIFOR (INTERNATIONAL) AG (CH) 2021-05-13 — — US disclosed
US-20210139472-A1 Novel Ferroportin Inhibitors VIFOR (INTERNATIONAL) AG (CH) 2021-05-13 — — US disclosed
US-11001579-B2 Ferroportin inhibitors VIFOR (INTERNATIONAL) AG (CH) 2021-05-11 — — US disclosed
US-20190345151-A1 Novel Ferroportin Inhibitors VIFOR (INTERNATIONAL) AG (CH) 2019-11-14 — — US disclosed
US-20190345151-A1 Novel Ferroportin Inhibitors VIFOR (INTERNATIONAL) AG (CH) 2019-11-14 — — US disclosed
US-10364239-B2 Ferroportin inhibitors VIFOR (INTERNATIONAL) AG (CH) 2019-07-30 — — US disclosed
US-20180319783-A1 Novel Ferroportin Inhibitors VIFOR (INTERNATIONAL) AG (CH) 2018-11-08 — — US disclosed
US-20180297991-A1 Novel Ferroportin Inhibitors VIFOR (INTERNATIONAL) AG (CH) 2018-10-18 — — US disclosed
EP-3365339-A1 NOVEL FERROPORTIN INHIBITORS Vifor (International) AG (CH) 2018-08-29 — — EP disclosed
EP-3364967-A2 FERROPORTIN INHIBITORS Vifor (International) AG (CH) 2018-08-29 — — EP disclosed
WO-2017068089-A2 NOVEL FERROPORTIN INHIBITORS VIFOR (INTERNATIONAL) AG (CH) 2017-04-27 — — WO disclosed
WO-2017068090-A1 NOVEL FERROPORTIN INHIBITORS VIFOR (INTERNATIONAL) AG (CH) 2017-04-27 — — WO disclosed
WO-2015190700-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING SEPSIS 성균관대학교산학협력단 2015-12-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190345151-A1 Novel Ferroportin Inhibitors HAMP, SLC40A1, HMOX1 ABCB1 269/4885KMT2A 2810/4885RAB9A 2934/4885
US-20210139472-A1 Novel Ferroportin Inhibitors HAMP, SLC40A1, HMOX1 ABCB1 269/4885KMT2A 2810/4885RAB9A 2934/4885
US-11066399-B2 Ferroportin inhibitors HAMP, SLC40A1, FTH1 ABCB1 215/4885KMT2A 3007/4885RAB9A 3011/4885
US-20180297991-A1 Novel Ferroportin Inhibitors SLC40A1, HAMP, TFRC ABCB1 153/4885KMT2A 4135/4885RAB9A 2357/4885
US-11001579-B2 Ferroportin inhibitors HAMP, SLC40A1, FTH1 ABCB1 215/4885KMT2A 3007/4885RAB9A 3011/4885
US-10364239-B2 Ferroportin inhibitors HAMP, SLC40A1, HMOX1 ABCB1 204/4885KMT2A 2451/4885RAB9A 2948/4885
US-20180319783-A1 Novel Ferroportin Inhibitors HAMP, SLC40A1, FTH1 ABCB1 295/4885KMT2A 2478/4885RAB9A 2983/4885
US-20220363675-A1 Novel Ferroportin Inhibitors HAMP, SLC40A1, HMOX1 ABCB1 269/4885KMT2A 2810/4885RAB9A 2934/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.