Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | ACP1 | P24666 | 3/20 | 0.41 |
| ▸ | CDC25B | P30305 | 3/20 | 0.41 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17351912 | 1.00 | PTPN1 (0.41) | PTPN1TDP1ACP1CDC25BHPSE | |
| SCHEMBL17356811 | 0.89 | PTPN1 (0.53) | PTPN1TDP1ACP1CDC25BHPSE | |
| SCHEMBL17356821 | 0.89 | PTPN1 (0.53) | PTPN1TDP1ACP1CDC25BHPSE | |
| SCHEMBL17356818 | 0.89 | PTPN1 (0.53) | PTPN1TDP1ACP1CDC25BHPSE | |
| SCHEMBL17356813 | 0.85 | PTPN1 (0.39) | PTPN1TDP1ACP1CDC25BHPSE | |
| SCHEMBL17356820 | 0.82 | PTPN1 (0.38) | PTPN1TDP1ACP1CDC25BHPSE | |
| Adipic Acid SCHEMBL6266341 | 0.63 | LMNA (0.48) | PTPN1TDP1HDAC11ABL1IDE | |
| SCHEMBL7329411 | 0.63 | TDP1 (0.46) | PTPN1TDP1HDAC11HDAC3HDAC4 | |
| Sebacic Acid SCHEMBL8734393 | 0.61 | TSHR (0.80) | PTPN1TDP1MAPTHDAC11PPARG | |
| Azelaic Acid SCHEMBL8066502 | 0.61 | TSHR (0.92) | PTPN1TDP1RECQLHDAC11PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209038-B | Osteopontin with dictyostelium discoideum pyrone derivative or dihydro dictyostelium discoideum pyrone derivative as active ingredient produces inhibitor | 国立大学法人东北大学 | 2017-06-09 | — | — | CN | disclosed |
| US-9463188-B2 | Osteopontin production inhibitor containing dictyopyrone derivative or dihydrodictyopyrone derivative as active ingredient | TOHOKU UNIVERSITY (JP) | 2016-10-11 | — | — | US | disclosed |
| CN-105209038-A | Osteopontin production inhibitor comprising dictyopyrone derivative or dihydrodictyopyrone derivative as active ingredient | UNIV TOHOKU NAT UNIV CORP | 2015-12-30 | — | — | CN | disclosed |
| US-20150366851-A1 | OSTEOPONTIN PRODUCTION INHIBITOR CONTAINING DICTYOPYRONE DERIVATIVE OR DIHYDRODICTYOPYRONE DERIVATIVE AS ACTIVE INGREDIENT | TOHOKU UNIVERSITY (JP) | 2015-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150366851-A1 | OSTEOPONTIN PRODUCTION INHIBITOR CONTAINING DICTYOPYRONE DERIVATIVE OR DIHYDRODICTYOPYRONE DERIVATIVE AS ACTIVE INGREDIENT | SPPL2B, DPYSL3, DIAPH1 | PTPN1 1624/4885TDP1 1952/4885ACP1 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.