Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | CCR2 | P41597 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17351999 | 0.98 | L3MBTL1 (0.52) | L3MBTL1CCR2HTTALDH1A1POLB | |
| SCHEMBL20520368 | 0.82 | L3MBTL1 (0.42) | L3MBTL1CCR2HTTALDH1A1POLB | |
| SCHEMBL23210378 | 0.77 | L3MBTL1 (0.55) | L3MBTL1CCR2HTTALDH1A1POLB | |
| SCHEMBL17352007 | 0.75 | L3MBTL1 (0.56) | L3MBTL1HTTALDH1A1POLBKLK5 | |
| SCHEMBL20292448 | 0.74 | EPHX1 (0.47) | ALDH1A1CYP1A2KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL20292466 | 0.74 | ALDH1A1 (0.49) | ALDH1A1CYP1A2KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL14811830 | 0.72 | L3MBTL1 (0.61) | L3MBTL1CCR2HTTALDH1A1POLB | |
| SCHEMBL14812115 | 0.72 | L3MBTL1 (0.61) | L3MBTL1CCR2HTTALDH1A1POLB | |
| SCHEMBL55591 | 0.72 | L3MBTL1 (0.61) | L3MBTL1CCR2HTTALDH1A1POLB | |
| SCHEMBL2792591 | 0.71 | L3MBTL1 (0.68) | L3MBTL1HTTALDH1A1POLBKLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015199987-A1 | SWEETENER ENHANCERS AND METHODS FOR USING THE SAME | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2015-12-30 | — | — | WO | disclosed |
| WO-2015199987-A1 | SWEETENER ENHANCERS AND METHODS FOR USING THE SAME | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2015-12-30 | — | — | WO | disclosed |
| US-20150366252-A1 | SWEETENER ENHANCERS AND METHODS FOR USING THE SAME | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2015-12-24 | — | — | US | disclosed |
| US-20150366252-A1 | SWEETENER ENHANCERS AND METHODS FOR USING THE SAME | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2015-12-24 | — | — | US | disclosed |
| US-20150366252-A1 | SWEETENER ENHANCERS AND METHODS FOR USING THE SAME | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2015-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150366252-A1 | SWEETENER ENHANCERS AND METHODS FOR USING THE SAME | TAS2R60, TAS1R1, TAS2R1 | L3MBTL1 1859/4885CCR2 2021/4885HTT 2858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.