Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12376717 | 0.91 | ACACB (0.47) | L3MBTL1ALDH1A1POLBHTTHSD17B10 | |
| SCHEMBL23210378 | 0.79 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1POLBHTTHSD17B10 | |
| SCHEMBL19586906 | 0.78 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1POLBHTTHSD17B10 | |
| SCHEMBL17351999 | 0.76 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1POLBHTTHSD17B10 | |
| SCHEMBL9307258 | 0.76 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1POLBHTTHSD17B10 | |
| SCHEMBL12409535 | 0.76 | ACACB (0.55) | L3MBTL1ALDH1A1HTTHSD17B10KMT2A | |
| SCHEMBL2789189 | 0.75 | L3MBTL1 (0.54) | L3MBTL1ALDH1A1POLBHTTHSD17B10 | |
| SCHEMBL17352003 | 0.75 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1POLBHTTHSD17B10 | |
| SCHEMBL14811830 | 0.74 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1POLBHTTHSD17B10 | |
| SCHEMBL55591 | 0.74 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1POLBHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015199987-A1 | SWEETENER ENHANCERS AND METHODS FOR USING THE SAME | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2015-12-30 | — | — | WO | disclosed |
| WO-2015199987-A1 | SWEETENER ENHANCERS AND METHODS FOR USING THE SAME | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2015-12-30 | — | — | WO | disclosed |
| US-20150366252-A1 | SWEETENER ENHANCERS AND METHODS FOR USING THE SAME | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2015-12-24 | — | — | US | disclosed |
| US-20150366252-A1 | SWEETENER ENHANCERS AND METHODS FOR USING THE SAME | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2015-12-24 | — | — | US | disclosed |
| US-20150366252-A1 | SWEETENER ENHANCERS AND METHODS FOR USING THE SAME | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2015-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150366252-A1 | SWEETENER ENHANCERS AND METHODS FOR USING THE SAME | TAS2R60, TAS1R1, TAS2R1 | L3MBTL1 1859/4885ALDH1A1 2410/4885POLB 4142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.