SCHEMBL1735430

SCHEMBL1735430

C(=Cc1ccc(Nc2nc(Nc3ccccc3)nc(N3CCOCC3)n2)cc1)c1ccc(Nc2nc(Nc3ccccc3)nc(N3CCOCC3)n2)cc1.[Na].[Na]

nearest known ligand 0.75

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.75
HTT P42858 1/20 0.75
CA12 O43570 4/20 0.69
CA1 P00915 4/20 0.69
CA2 P00918 4/20 0.69
CA9 Q16790 4/20 0.69
POLB P06746 3/20 0.65
MAPT P10636 5/20 0.64
SMN1; SMN2 Q16637 2/20 0.60
CYP1A2 P05177 1/20 0.60
CYP3A4 P08684 1/20 0.60
CYP2C9 P11712 1/20 0.60
CYP2C19 P33261 1/20 0.60
TP53 P04637 1/20 0.58
KMT2A Q03164 4/20 0.56
MEN1 O00255 2/20 0.56
PTGS2 P35354 2/20 0.56
NPSR1 Q6W5P4 2/20 0.55
GAA P10253 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3115297 0.99 LMNA (0.77) LMNAHTTCA12CA1CA2
SCHEMBL757098 0.99 LMNA (0.77) LMNAHTTCA12CA1CA2
SCHEMBL30139086 0.99 LMNA (0.77) LMNAHTTCA12CA1CA2
SCHEMBL3880764 0.97 LMNA (0.75) LMNAHTTCA12CA1CA2
SCHEMBL8925967 0.97 LMNA (0.75) LMNAHTTCA12CA1CA2
SCHEMBL29345146 0.89 LMNA (0.94) LMNAHTTCA12CA1CA2
SCHEMBL11810697 0.86 LMNA (1.00) LMNAHTTCA12CA1CA2
SCHEMBL18796549 0.86 LMNA (0.65) LMNAHTTCA12CA1CA2
SCHEMBL6740369 0.84 LMNA (0.78) LMNAHTTCA12CA1CA2
SCHEMBL11876083 0.84 PTGS2 (0.62) LMNAHTTCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 279 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10457894-B2 Color-protecting detergent or cleaning agent having an optical brightener HENKEL AG & CO. KGAA (DE) 2019-10-29 US claimed
EP-2976415-B1 COLOUR PROTECTING DETERGENT COMPOPOSITION COMPRISING AN OPTICAL BRIGHTENER HENKEL AG & CO KGAA (DE) 2018-10-17 EP claimed
US-20160010030-A1 COLOR-PROTECTING DETERGENT OR CLEANING AGENT HAVING AN OPTICAL BRIGHTENER HENKEL AG & CO. KGAA (DE) 2016-01-14 US claimed
EP-2176392-B1 COLOR-SAFE DETERGENT OR CLEANING AGENT HAVING OPTICAL BRIGHTENER HENKEL AG & CO KGAA (DE) 2013-10-23 EP claimed
US-20100144579-A1 Color-Safe Detergent or Cleaning Agent having Optical Brightener HENKEL AG & CO. KGAA (DE) 2010-06-10 US claimed
EP-4176037-B1 UNIT DOSE CAPSULE UNILEVER IP HOLDINGS B V (NL) 2024-03-13 EP disclosed
EP-4176036-B1 A UNIT DOSE CAPSULE UNILEVER IP HOLDINGS B V (NL) 2024-03-13 EP disclosed
US-11873468-B2 Polymers for the treatment of surfaces HENKEL AG & CO. KGAA (DE) 2024-01-16 US disclosed
WO-2023186459-A1 HAIR REMOVAL BY MEANS OF DETERGENT/DETERGENT ADDITIVES CONTAINING ENZYMES HENKEL AG & CO. KGAA (DE) 2023-10-05 WO disclosed
US-20230313086-A1 A UNIT DOSE CAPSULE CONOPCO, INC., D/B/A UNILEVER (US) 2023-10-05 US disclosed
US-20230313085-A1 UNIT DOSE CAPSULE Conopco, lnc., d/b/a UNILEVER (US) 2023-10-05 US disclosed
US-20230235255-A1 A UNIT DOSE CAPSULE CONOPCO, INC. D/B/A UNILEVER (US) 2023-07-27 US disclosed
US-5160654-A Two-compartment sachet, bleaching detergent, sodium percarbonate, cholyl 4-sulfophenyl carbonate activator LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1992-11-03 US disclosed
US-5132036-A Pouches which release bleach and detergent during laundering LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1992-07-21 US disclosed
EP-0481792-A1 Detergent compositions in tablet form UNILEVER PLC (GB) 1992-04-22 EP disclosed
EP-0481793-A1 Detergent composition in tablet form UNILEVER PLC (GB) 1992-04-22 EP disclosed
EP-0466485-A2 Detergent compositions UNILEVER PLC (GB) 1992-01-15 EP disclosed
EP-0466484-A2 Detergent compositions UNILEVER PLC (GB) 1992-01-15 EP disclosed
EP-0414462-A2 Laundry treatment product UNILEVER PLC (GB) 1991-02-27 EP disclosed
EP-0395333-A2 Detergent compositions UNILEVER PLC (GB) 1990-10-31 EP disclosed