SCHEMBL3880764

SCHEMBL3880764

C(=Cc1ccc(Nc2nc(Nc3ccccc3)nc(N3CCOCC3)n2)cc1)c1ccc(Nc2nc(Nc3ccccc3)nc(N3CCOCC3)n2)cc1.[NaH].[NaH]

nearest known ligand 0.75

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.75
HTT P42858 1/20 0.75
CA12 O43570 3/20 0.65
CA1 P00915 3/20 0.65
CA2 P00918 3/20 0.65
CA9 Q16790 3/20 0.65
POLB P06746 3/20 0.65
MAPT P10636 5/20 0.64
SMN1; SMN2 Q16637 2/20 0.60
CYP1A2 P05177 1/20 0.60
CYP3A4 P08684 1/20 0.60
CYP2C9 P11712 1/20 0.60
CYP2C19 P33261 1/20 0.60
TP53 P04637 1/20 0.58
KMT2A Q03164 5/20 0.56
MEN1 O00255 3/20 0.56
PTGS2 P35354 2/20 0.56
NPSR1 Q6W5P4 2/20 0.55
GAA P10253 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8925967 1.00 LMNA (0.75) LMNAHTTCA12CA1CA2
SCHEMBL3115297 0.99 LMNA (0.77) LMNAHTTCA12CA1CA2
SCHEMBL757098 0.99 LMNA (0.77) LMNAHTTCA12CA1CA2
SCHEMBL30139086 0.99 LMNA (0.77) LMNAHTTCA12CA1CA2
SCHEMBL1735430 0.97 LMNA (0.75) LMNAHTTCA12CA1CA2
SCHEMBL29345146 0.89 LMNA (0.94) LMNAHTTCA12CA1CA2
SCHEMBL11810697 0.86 LMNA (1.00) LMNAHTTCA12CA1CA2
SCHEMBL11876083 0.86 PTGS2 (0.62) LMNAHTTCA12CA1CA2
SCHEMBL18796549 0.86 LMNA (0.65) LMNAHTTCA12CA1CA2
SCHEMBL8746487 0.84 CA12 (0.56) LMNAHTTCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017072788-A1 IMPROVED OPTICAL BRIGHTENING AGENT FOR DETERGENT FORMULATIONS AND A PROCESS FOR PREPARING THE SAME DEEPAK NITRITE LIMITED (IN) 2017-05-04 WO claimed
WO-2023186459-A1 HAIR REMOVAL BY MEANS OF DETERGENT/DETERGENT ADDITIVES CONTAINING ENZYMES HENKEL AG & CO. KGAA (DE) 2023-10-05 WO disclosed
EP-3749739-B1 DETERGENT COMPOSITION HAVING A FLOW LIMIT HENKEL AG & CO KGAA (DE) 2023-06-21 EP disclosed
EP-3947615-B1 USE OF A MANNANASE ENZYME IN COMBINATION WITH CATECHOL DERIVATIVES HENKEL AG & CO KGAA (DE) 2023-04-05 EP disclosed
CN-115135693-A Alkoxylated polyamines with improved biodegradability 巴斯夫股份公司 2022-09-30 CN disclosed
CN-115003785-A Cleaning composition 宝洁公司 2022-09-02 CN disclosed
US-11421048-B2 Dual activated microgel LUBRIZOL ADVANCED MATERIALS, INC. (US) 2022-08-23 US disclosed
CN-110225966-B Water-soluble unit dose articles comprising water-soluble fibrous structures and particles 宝洁公司 2022-04-05 CN disclosed
CN-114269841-A Film 联合利华知识产权控股有限公司 2022-04-01 CN disclosed
CN-110214172-B Water-soluble unit dose articles comprising water-soluble fibrous structures and particles 宝洁公司 2021-08-31 CN disclosed
EP-1693441-B1 A particulate laundry detergent composition comprising a detersive surfactant, carbonate and a fluorescent whitening component PROCTER & GAMBLE (US) 2009-01-07 EP disclosed
EP-1693441-A1 A particulate laundry detergent composition comprising a detersive surfactant, carbonate and a fluorescent whitening component THE PROCTER & GAMBLE COMPANY (US) 2006-08-23 EP disclosed
US-5658874-A Production of detergent tablet compositions LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1997-08-19 US disclosed
US-5160654-A Two-compartment sachet, bleaching detergent, sodium percarbonate, cholyl 4-sulfophenyl carbonate activator LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1992-11-03 US disclosed
US-5132036-A Pouches which release bleach and detergent during laundering LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1992-07-21 US disclosed
EP-0167205-B1 STABLE LIQUID DETERGENTS CONTAINING ANIONIC SURFACTANT AND MONOSULFONATED BRIGHTENER THE PROCTER & GAMBLE COMPANY (US) 1992-03-11 EP disclosed
US-4978475-A REDUCING BRIGHTENER STAINING THE PROCTER & GAMBLE COMPANY (US) 1990-12-18 US disclosed
US-4970029-A MONOSULFONATED NAPHTHOTRIAZINE STILBENE BRIGHTENER THE PROCTER & GAMBLE COMPANY (US) 1990-11-13 US disclosed
EP-0167205-A2 Stable liquid detergents containing anionic surfactant and monosulfonated brightener THE PROCTER & GAMBLE COMPANY (US) 1986-01-08 EP disclosed
US-4559169-A STILBENE SULFONATE DERIVATIVES THE PROCTER & GAMBLE COMPANY (US) 1985-12-17 US disclosed