Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.75 |
| ▸ | HTT | P42858 | 1/20 | 0.75 |
| ▸ | CA12 | O43570 | 3/20 | 0.65 |
| ▸ | CA1 | P00915 | 3/20 | 0.65 |
| ▸ | CA2 | P00918 | 3/20 | 0.65 |
| ▸ | CA9 | Q16790 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3880764 | 1.00 | LMNA (0.75) | LMNAHTTCA12CA1CA2 | |
| SCHEMBL3115297 | 0.99 | LMNA (0.77) | LMNAHTTCA12CA1CA2 | |
| SCHEMBL757098 | 0.99 | LMNA (0.77) | LMNAHTTCA12CA1CA2 | |
| SCHEMBL30139086 | 0.99 | LMNA (0.77) | LMNAHTTCA12CA1CA2 | |
| SCHEMBL1735430 | 0.97 | LMNA (0.75) | LMNAHTTCA12CA1CA2 | |
| SCHEMBL29345146 | 0.89 | LMNA (0.94) | LMNAHTTCA12CA1CA2 | |
| SCHEMBL11810697 | 0.86 | LMNA (1.00) | LMNAHTTCA12CA1CA2 | |
| SCHEMBL11876083 | 0.86 | PTGS2 (0.62) | LMNAHTTCA12CA1CA2 | |
| SCHEMBL18796549 | 0.86 | LMNA (0.65) | LMNAHTTCA12CA1CA2 | |
| SCHEMBL8746487 | 0.84 | CA12 (0.56) | LMNAHTTCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3947615-B1 | USE OF A MANNANASE ENZYME IN COMBINATION WITH CATECHOL DERIVATIVES | HENKEL AG & CO KGAA (DE) | 2023-04-05 | — | — | EP | disclosed |
| US-11421048-B2 | Dual activated microgel | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2022-08-23 | — | — | US | disclosed |
| US-5658874-A | Production of detergent tablet compositions | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1997-08-19 | — | — | US | disclosed |