SCHEMBL17355693

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14872750	0.85	CA1 (0.52)	CA1CA2CA9PTGS2PTGS1
	SCHEMBL32665346	0.85	CA1 (0.47)	CA1CA2CA9PTGS2PTGS1
	SCHEMBL4121195	0.83	CA1 (0.46)	CA1CA2CA9PTGS2PTGS1
	SCHEMBL3843216	0.82	PTGS2 (0.47)	CA2PTGS2PTGS1
	SCHEMBL3746820	0.82	PTGS2 (0.43)	PTGS2PTGS1KMT2AKDM4EHPGD
	SCHEMBL6937925	0.80	CA1 (0.55)	CA1CA2CA9KMT2AKDM4E
	SCHEMBL8756177	0.79	L3MBTL1 (0.39)	CA1CA2CA9PTGS2PTGS1
	SCHEMBL16680513	0.79	PPARG (0.46)	PTGS2PTGS1MRGPRX4HTTALDH1A1
	SCHEMBL9958393	0.78	ACHE (0.65)	CA1CA2CA9KMT2ATSHR
	SCHEMBL9957777	0.78	GAA (0.47)	CA1CA2CA9PTGS2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.