SCHEMBL17356498

SCHEMBL17356498

COC(=O)C(=O)Oc1cc(F)cc(C(F)(F)F)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 2/20 0.44
SCN9A Q15858 1/20 0.43
NOTUM Q6P988 1/20 0.40
TLR8 Q9NR97 1/20 0.39
CYP4F2 P78329 1/20 0.37
CYP4A11 Q02928 1/20 0.37
RXRA P19793 2/20 0.36
RXRB P28702 2/20 0.36
RXRG P48443 2/20 0.36
ADCY8 P40145 1/20 0.36
ADCY1 Q08828 1/20 0.36
MAPT P10636 1/20 0.36
CYP3A4 P08684 1/20 0.36
HTT P42858 1/20 0.36
CFTR P13569 1/20 0.36
HDAC3 O15379 2/20 0.35
HDAC1 Q13547 2/20 0.35
HDAC2 Q92769 2/20 0.35
HDAC6 Q9UBN7 2/20 0.35
P2RX1 P51575 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17356468 0.85 SCN9A (0.46) GPR35SCN9ANOTUMTLR8CYP4F2
SCHEMBL17356485 0.81 CYP4F2 (0.56) SCN9ANOTUMTLR8CYP4F2CYP4A11
SCHEMBL5245392 0.78 KIF11 (0.53) SCN9ATLR8CYP4F2CYP4A11RXRA
SCHEMBL17355792 0.78 CYP4F2 (0.40) CYP4F2CYP4A11MAPTHDAC3HDAC1
SCHEMBL1295615 0.77 SCN9A (0.43) GPR35SCN9ANOTUMTLR8CYP4F2
SCHEMBL17356471 0.77 GPR35 (0.46) GPR35NOTUMTLR8MAPTCFTR
SCHEMBL17356453 0.77 SOS1 (0.37) GPR35NOTUMMAPTCFTRMAPK1
SCHEMBL2522090 0.75 RXRA (0.43) SCN9ARXRARXRBRXRGADCY8
SCHEMBL30181252 0.75 RXRA (0.43) SCN9ARXRARXRBRXRGADCY8
SCHEMBL15453564 0.74 CES2 (0.45) GPR35SCN9ANOTUMRXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE UBE INDUSTRIES, LTD. (JP) 2015-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE HCN2, SCO2, HCN1 GPR35 3738/4885SCN9A 172/4885NOTUM 723/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.