SCHEMBL17356785

SCHEMBL17356785

COc1cccc(C)c1C1CCCC(c2ccccc2)C1C

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 7/20 0.38
DRD2 P14416 1/20 0.38
KDM1A O60341 5/20 0.37
MAOA P21397 5/20 0.37
MAOB P27338 3/20 0.37
FABP7 O15540 1/20 0.37
FABP3 P05413 1/20 0.37
FABP5 Q01469 1/20 0.37
HCRTR1 O43613 2/20 0.37
HCRTR2 O43614 2/20 0.37
EPHX2 P34913 1/20 0.37
TACR1 P25103 1/20 0.36
ABCB1 P08183 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17356807 0.91 HTR1A (0.40) HTR1ADRD2HCRTR1HCRTR2ABCB1
SCHEMBL17356787 0.86 HTR2C (0.40)
SCHEMBL17356790 0.80 FABP7 (0.48) KDM1AMAOAMAOBFABP7FABP3
SCHEMBL17356791 0.78 ABCB1 (0.42) HTR1ADRD2HCRTR1HCRTR2ABCB1
SCHEMBL17356802 0.77 PNMT (0.38) EPHX2TACR1
SCHEMBL17356788 0.71 HTR2C (0.50) DRD2
SCHEMBL17356793 0.71 ABCB1 (0.43) HTR1ADRD2ABCB1
SCHEMBL16955777 0.70 ABCB1 (0.53) HTR1ADRD2HCRTR1HCRTR2ABCB1
SCHEMBL10914783 0.69 MAOB (0.48) HTR1AKDM1AMAOAMAOB
SCHEMBL5680394 0.68 MEN1 (0.43) HTR1AKDM1AMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170313792-A1 METHOD FOR PRODUCING POLAR GROUP-CONTAINING OLEFIN POLYMER THE UNIVERSITY OF TOKYO (JP) 2017-11-02 US disclosed
US-9499644-B2 Production method of polar group-containing olefin polymers SHOWA DENKO K.K. (JP) 2016-11-22 US disclosed
US-20150368376-A1 PRODUCTION METHOD OF POLAR GROUP-CONTAINING OLEFIN POLYMERS SHOWA DENKO K.K. (JP) 2015-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150368376-A1 PRODUCTION METHOD OF POLAR GROUP-CONTAINING OLEFIN POLYMERS OR10J3, OPRM1, ORC3 HTR1A 3188/4885DRD2 1606/4885KDM1A 2500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.