SCHEMBL17356802

SCHEMBL17356802

Cc1cccc(C(F)(F)F)c1C1CCCC(c2ccccc2)C1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.38
TACR1 P25103 1/20 0.34
EPHX2 P34913 1/20 0.33
TAS1R3 Q7RTX0 1/20 0.33
TAS1R1 Q7RTX1 1/20 0.33
TAS1R2 Q8TE23 1/20 0.33
SLC6A2 P23975 2/20 0.33
SLC6A3 Q01959 1/20 0.33
SLC6A1 P30531 1/20 0.32
CCR5 P51681 1/20 0.32
GAA P10253 3/20 0.32
GRIA4 P48058 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
ATM Q13315 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
CHRNB2 P17787 1/20 0.32
CHRNA4 P43681 1/20 0.32
TAS2R14 Q9NYV8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17356805 0.92 PNMT (0.43) PNMTTAS1R3TAS1R1TAS1R2SLC6A2
SCHEMBL17356803 0.86 PNMT (0.43) PNMTTAS1R3TAS1R1TAS1R2GAA
SCHEMBL17356796 0.80 HTR2C (0.43) PNMTTACR1CCR5GAAGRIA4
SCHEMBL17356789 0.79 TAS1R3 (0.44) PNMTEPHX2TAS1R3TAS1R1TAS1R2
SCHEMBL17356785 0.77 HTR1A (0.38) TACR1EPHX2
SCHEMBL17356809 0.71 PNMT (0.46) PNMTTAS1R3TAS1R1TAS1R2SLC6A2
SCHEMBL17356801 0.71 HTR2C (0.49) PNMTTAS1R3TAS1R1TAS1R2SLC6A2
SCHEMBL10914783 0.68 MAOB (0.48) SLC6A2SLC6A3MEN1KMT2A
SCHEMBL5680394 0.67 MEN1 (0.43) SLC6A2SLC6A3GRIA4MEN1KMT2A
SCHEMBL17356807 0.66 HTR1A (0.40) TAS1R3TAS1R1TAS1R2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170313792-A1 METHOD FOR PRODUCING POLAR GROUP-CONTAINING OLEFIN POLYMER THE UNIVERSITY OF TOKYO (JP) 2017-11-02 US disclosed
US-9499644-B2 Production method of polar group-containing olefin polymers SHOWA DENKO K.K. (JP) 2016-11-22 US disclosed
US-20150368376-A1 PRODUCTION METHOD OF POLAR GROUP-CONTAINING OLEFIN POLYMERS SHOWA DENKO K.K. (JP) 2015-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150368376-A1 PRODUCTION METHOD OF POLAR GROUP-CONTAINING OLEFIN POLYMERS OR10J3, OPRM1, ORC3 PNMT 316/4885TACR1 834/4885EPHX2 640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.