Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 3/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PAM | P19021 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33770 | 0.88 | DGKA (0.50) | DGKALMNAKDM4EDUSP3MEN1 | |
| SCHEMBL14830029 | 0.86 | DGKA (0.44) | DGKALMNAMAPTTSHRALDH1A1 | |
| SCHEMBL14830615 | 0.85 | MAPT (0.41) | DGKALMNAMAPTTSHRALDH1A1 | |
| SCHEMBL2119253 | 0.83 | MGLL (0.49) | DGKALMNAKDM4EDUSP3MAPT | |
| Palmitic Acid SCHEMBL8518708 | 0.83 | FFAR4 (0.53) | DGKAMEN1KMT2AMAPTTSHR | |
| SCHEMBL11747177 | 0.80 | LMNA (0.42) | LMNAMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL29109107 | 0.80 | DGKA (0.47) | DGKALMNAKDM4EDUSP3MEN1 | |
| SCHEMBL31065847 | 0.80 | LMNA (0.50) | DGKALMNAKDM4EDUSP3MEN1 | |
| SCHEMBL29277359 | 0.79 | LMNA (0.51) | DGKALMNAKDM4EDUSP3MEN1 | |
| SCHEMBL29128054 | 0.79 | LMNA (0.51) | DGKALMNAKDM4EDUSP3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190321329-A1 | FORMULATION FOR THE TREATMENT OF ACNE | AKZO NOBEL CHEMICALS INT BV (NL) | 2019-10-24 | — | — | US | disclosed |
| EP-3340975-B1 | FORMULATION FOR THE TREATMENT OF ACNE | AKZO NOBEL CHEMICALS INT BV (NL) | 2019-07-24 | — | — | EP | disclosed |
| US-10278945-B2 | Formulation for the treatment of acne | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2019-05-07 | — | — | US | disclosed |
| US-20190022050-A1 | FORMULATION FOR THE TREATMENT OF ACNE | NOURYON CHEMICALS INTERNATIONAL B.V. (NL) | 2019-01-24 | — | — | US | disclosed |
| EP-3340975-A1 | FORMULATION FOR THE TREATMENT OF ACNE | Akzo Nobel Chemicals International B.V. (NL) | 2018-07-04 | — | — | EP | disclosed |
| US-20170156999-A1 | PERSONAL CARE COMPOSITION IN A DISSOLVABLE CONTAINER | Henkel IP & Holding GmbH (DE) | 2017-06-08 | — | — | US | disclosed |
| WO-2017036897-A1 | FORMULATION FOR THE TREATMENT OF ACNE | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2017-03-09 | — | — | WO | disclosed |
| WO-2016110872-A1 | FOOT CARE COMPOSITIONS | Zydus Wellness Limited (IN) | 2016-07-14 | — | — | WO | disclosed |
| US-9072675-B2 | Non-irritating benzoyl peroxide | ESSENTIAL INGREDIENTS, INC. (US) | 2015-07-07 | — | — | US | disclosed |
| US-20140161853-A1 | Non-Irritating Benzoyl Peroxide | ESSENTIAL INGREDIENTS, INC. (US) | 2014-06-12 | — | — | US | disclosed |
| US-8697130-B1 | Non-irritating benzoyl peroxide | ESSENTIAL INGREDIENTS, INC. (US) | 2014-04-15 | — | — | US | disclosed |
| EP-2172185-B1 | Cosmetic material comprising octyl hydroxy stearate oligomer | PARAHERMOSA CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |
| US-20100111884-A1 | UV ABSORBER FORMULATIONS | CIBA CORPORATION (US) | 2010-05-06 | — | — | US | disclosed |
| US-20090196894-A1 | Self Tanning Composition | CIBA CORP. | 2009-08-06 | — | — | US | disclosed |
| EP-2026746-A2 | SELF TANNING COMPOSITION | Ciba Holding Inc. (CH) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007137958-A2 | SELF TANNING COMPOSITION | CIBA HOLDING INC. (CH) | 2007-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100111884-A1 | UV ABSORBER FORMULATIONS | C1R, C1S, C9 | DGKA 4376/4885LMNA 1485/4885KDM4E 1391/4885 |
| US-20090196894-A1 | Self Tanning Composition | C9, KRT18, F12 | DGKA 2047/4885LMNA 657/4885KDM4E 373/4885 |
| US-20190321329-A1 | FORMULATION FOR THE TREATMENT OF ACNE | ACOX1, HSD17B12, ACOX3 | DGKA 2278/4885LMNA 4226/4885KDM4E 3881/4885 |
| US-20190022050-A1 | FORMULATION FOR THE TREATMENT OF ACNE | ACOX1, HSD17B12, ACOX3 | DGKA 2278/4885LMNA 4226/4885KDM4E 3881/4885 |
| US-10278945-B2 | Formulation for the treatment of acne | ACOX1, HSD17B12, ACOX3 | DGKA 2278/4885LMNA 4226/4885KDM4E 3881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.