SCHEMBL17358728

SCHEMBL17358728

CC1C(=O)N(c2ccccc2)C(=O)N(c2ccccc2)C1=O

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.53
LOX P28300 1/20 0.47
LOXL3 P58215 1/20 0.47
LOXL4 Q96JB6 1/20 0.47
LOXL2 Q9Y4K0 1/20 0.47
CACNA1B Q00975 1/20 0.47
APBA1 Q02410 1/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
MGLL Q99685 1/20 0.46
SMO Q99835 2/20 0.45
GAA P10253 2/20 0.45
G6PD P11413 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
POLB P06746 1/20 0.44
ATM Q13315 1/20 0.44
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17717952 0.88 SMO (0.48) MAOALOXLOXL3LOXL4LOXL2
SCHEMBL15978112 0.78 MEN1 (0.53) MAOACACNA1BAPBA1MEN1KMT2A
SCHEMBL11182628 0.78 MGLL (0.62) MEN1KMT2AMGLLGAAALDH1A1
SCHEMBL13879393 0.78 SMO (0.49) MAOACACNA1BAPBA1MEN1KMT2A
SCHEMBL17358727 0.78 CES2 (0.49) MAOACACNA1BAPBA1MEN1KMT2A
SCHEMBL19923522 0.78 SMO (0.53) MAOACACNA1BAPBA1MEN1KMT2A
SCHEMBL9923584 0.77 MEN1 (0.57) MAOALOXLOXL3LOXL4LOXL2
SCHEMBL12900984 0.77 LMNA (0.50) MAOALOXLOXL3LOXL4LOXL2
SCHEMBL10031597 0.77 MEN1 (0.57) MAOALOXLOXL3LOXL4LOXL2
SCHEMBL1639999 0.77 ALDH1A1 (0.47) MAOACACNA1BAPBA1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10338290-B2 Cellulose ester film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2019-07-02 US disclosed
US-9551813-B2 Optical film, polarizing plate using same, and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-01-24 US disclosed
US-9551813-B2 Optical film, polarizing plate using same, and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-01-24 US disclosed
US-20160370522-A1 CELLULOSE ESTER FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-12-22 US disclosed
US-20160370522-A1 CELLULOSE ESTER FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-12-22 US disclosed
US-20150369960-A1 OPTICAL FILM, POLARIZING PLATE USING SAME, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-12-24 US disclosed
US-20150369960-A1 OPTICAL FILM, POLARIZING PLATE USING SAME, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-12-24 US disclosed