Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17359608 | 0.86 | PLA2G2A (0.37) | PLA2G2APLA2G10PLA2G1BPLA2G5KIF11 | |
| SCHEMBL17359778 | 0.73 | PLA2G2A (0.36) | PLA2G2APLA2G10PLA2G1BPLA2G5KIF11 | |
| SCHEMBL18609340 | 0.71 | PLA2G2A (0.49) | PLA2G2APLA2G10PLA2G1BPLA2G5KIF11 | |
| SCHEMBL15895168 | 0.69 | PLA2G2A (0.38) | PLA2G2APLA2G10PLA2G1BPLA2G5KIF11 | |
| SCHEMBL15895042 | 0.68 | PLA2G2A (0.40) | PLA2G2APLA2G10PLA2G1BPLA2G5KIF11 | |
| SCHEMBL17359776 | 0.67 | PLA2G2A (0.39) | PLA2G2APLA2G10PLA2G1BPLA2G5KIF11 | |
| SCHEMBL3398385 | 0.67 | KIF11 (0.59) | KIF11 | |
| SCHEMBL18912718 | 0.67 | PLA2G2A (0.55) | PLA2G2APLA2G10PLA2G1BPLA2G5KIF11 | |
| SCHEMBL8356181 | 0.66 | PLA2G2A (0.53) | PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL8353837 | 0.66 | PLA2G2A (0.53) | PLA2G2APLA2G10PLA2G1BPLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150366887-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | Janssen Pharmaceuticals, Inc. | 2015-12-24 | — | — | US | disclosed |
| US-20150366888-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | Janssen Pharmaceuticals, Inc. | 2015-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150366888-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | PNP, NT5C3B, TYMP | PLA2G2A 4329/4885PLA2G10 4148/4885PLA2G1B 3940/4885 |
| US-20150366887-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | PNP, NUDT1, NT5C3B | PLA2G2A 2939/4885PLA2G10 2487/4885PLA2G1B 2210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.