Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 9/20 | 0.47 |
| ▸ | MMP9 | P14780 | 6/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | EEF2K | O00418 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15916274 | 0.89 | GBA1 (0.53) | MMP2MMP9ADAMTS4ALDH1A1SLC1A3 | |
| Trifluoroacetic Acid SCHEMBL7346536 | 0.77 | ADAMTS4 (0.68) | MMP2MMP9ADAMTS4ALDH1A1MAPT | |
| SCHEMBL7401946 | 0.76 | MMP2 (0.50) | MMP2MMP9ADAMTS4ALDH1A1SLC1A3 | |
| Trifluoroacetic Acid SCHEMBL27626580 | 0.75 | CA1 (0.50) | ALOX15MMP2MMP9ALDH1A1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL2224180 | 0.74 | NR3C2 (0.54) | MMP2MMP9ALDH1A1CA12CA9 | |
| Trifluoroacetic Acid SCHEMBL1805155 | 0.74 | NR3C2 (0.54) | MMP2MMP9ALDH1A1CA12CA9 | |
| Trifluoroacetic Acid SCHEMBL15918326 | 0.74 | GAA (0.56) | ALOX15MMP2MMP9ALDH1A1MAPT | |
| Trifluoroacetic Acid SCHEMBL15012437 | 0.73 | MMP1 (0.66) | MMP2MMP9ALDH1A1F2TMPRSS6 | |
| Trifluoroacetic Acid SCHEMBL27131035 | 0.72 | REN (0.47) | ALOX15MMP2MMP9MMP1MMP3 | |
| SCHEMBL9257309 | 0.72 | NPSR1 (0.44) | MMP9ADAMTS4ALDH1A1MAPTEEF2K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745328-B2 | Flap modulators | JANSSEN PHARMACEUTICA NV (BE) | 2017-08-29 | — | — | US | disclosed |
| US-20150376212-A1 | FLAP MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150376212-A1 | FLAP MODULATORS | FEN1, PGF, TBXA2R | ALOX15 74/4885MMP2 916/4885MMP9 706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.