Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.50 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 8/20 | 0.47 |
| ▸ | CDK1 | P06493 | 7/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 7/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 7/20 | 0.44 |
| ▸ | CCNA1 | P78396 | 7/20 | 0.44 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 5/20 | 0.44 |
| ▸ | MGMT | P16455 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17364327 | 0.82 | XDH (0.44) | DPP4PNPADORA2AADORA1CA12 | |
| SCHEMBL3773144 | 0.78 | HRH4 (0.56) | DPP4HRH4PDPK1GDACDK2 | |
| SCHEMBL17364285 | 0.77 | CA12 (0.61) | HRH4PDPK1MAP3K5LMNATSHR | |
| SCHEMBL17364330 | 0.77 | ADORA2A (0.40) | DPP4HRH4PNPADORA2AADORA1 | |
| SCHEMBL3780112 | 0.77 | HRH4 (0.51) | DPP4HRH4PDPK1GDACDK2 | |
| SCHEMBL38942 | 0.73 | HRH4 (0.85) | DPP4HRH4PDPK1GDACDK2 | |
| 6-Chloroguanine SCHEMBL64059 | 0.69 | DPP4 (1.00) | DPP4HRH4PDPK1GDACDK2 | |
| SCHEMBL2867588 | 0.69 | PDPK1 (0.66) | DPP4HRH4PDPK1GDACDK2 | |
| 2,6-Diaminopurine SCHEMBL24053 | 0.68 | PDPK1 (1.00) | DPP4HRH4PDPK1GDACDK2 | |
| Hydrochloric Acid SCHEMBL7290518 | 0.68 | HRH4 (0.70) | DPP4HRH4PDPK1GDACDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150376219-A1 | Selective Preparations of Purine Nucleosides and Nucleotides: Reagents and Methods | ZHONG MINGHONG (US) | 2015-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150376219-A1 | Selective Preparations of Purine Nucleosides and Nucleotides: Reagents and Methods | PNP, ATIC, NT5C3B | DPP4 293/4885HRH4 1594/4885PDPK1 939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.