Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K2 | P36507 | 2/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12030950 | 0.82 | MAP2K1 (0.33) | MAP2K2MAP2K1 | |
| SCHEMBL17366279 | 0.77 | IDO1 (0.30) | — | |
| SCHEMBL13107429 | 0.76 | CES2 (0.43) | — | |
| SCHEMBL7097753 | 0.73 | PPARG (0.38) | — | |
| SCHEMBL14140533 | 0.73 | NFE2L2 (0.36) | — | |
| SCHEMBL29481423 | 0.69 | — | — | |
| SCHEMBL80458 | 0.69 | — | — | |
| SCHEMBL2038516 | 0.69 | — | — | |
| Fluoride SCHEMBL25169957 | 0.67 | CES2 (0.39) | MAP2K2MAP2K1 | |
| SCHEMBL31621665 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588451-B1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INT (DE) | 2015-12-30 | — | — | EP | disclosed |