Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21791937 | 0.84 | ALDH1A1 (0.36) | PPARGPPARAKMT2AHSD17B10TSHR | |
| SCHEMBL27678216 | 0.77 | CYP3A4 (0.41) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| SCHEMBL21737149 | 0.77 | CCR2 (0.34) | PPARGPPARAKMT2ATSHRALDH1A1 | |
| SCHEMBL14261346 | 0.76 | TSHR (0.48) | KMT2AHSD17B10TSHRALDH1A1CYP3A4 | |
| SCHEMBL13107429 | 0.76 | CES2 (0.43) | KMT2AALDH1A1TDP1ALOX12 | |
| SCHEMBL14140533 | 0.73 | NFE2L2 (0.36) | KMT2AHSD17B10ALDH1A1CYP3A4TDP1 | |
| SCHEMBL17366292 | 0.73 | MAP2K2 (0.33) | — | |
| SCHEMBL530450 | 0.72 | — | — | |
| SCHEMBL29443091 | 0.72 | — | — | |
| SCHEMBL13300191 | 0.71 | TSHR (0.48) | KMT2AHSD17B10TSHRALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230134932-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2023-05-04 | — | — | US | disclosed |
| US-20230134932-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2023-05-04 | — | — | US | disclosed |
| US-11239426-B2 | Electroactive compounds | LG CHEM, LTD. | 2022-02-01 | — | — | US | disclosed |
| WO-2021238587-A1 | MICROMOLECULAR OXATHIAZINE DERIVATIVE AND USE THEREOF | 四川大学华西医院 | 2021-12-02 | — | — | WO | disclosed |
| WO-2018097937-A1 | ELECTROACTIVE COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2018-05-31 | — | — | WO | disclosed |
| CN-102428064-A | Novel pesticide | SYNGENTA LTD | 2012-04-25 | — | — | CN | disclosed |
| CN-1972695-A | Treatment or prevention of skin conditions or tissue conditions in animals using boryloxypyridylmethanones | ANACOR PHARMACEUTICALS INC (US) | 2007-05-30 | — | — | CN | disclosed |
| EP-1339725-A2 | DNA METHYL TRANSFERASE INHIBITORS | THE PENN STATE RESEARCH FOUNDATION (US) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002044184-A2 | DNA METHYL TRANSFERASE INHIBITORS | THE PENN STATE RESEARCH FOUNDATION (US) | 2002-06-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230134932-A1 | EIF4E INHIBITORS AND USES THEREOF | EIF4E, EIF4EBP1, EIF4A1 | PPARG 4693/4885PPARA 4678/4885KMT2A 1931/4885 |
| US-11239426-B2 | Electroactive compounds | KCNN2, HCN2, KCNN3 | PPARG 1259/4885PPARA 1817/4885KMT2A 3000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.