Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13291598 | 0.84 | MAOB (0.44) | HTTALDH1A1CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL10938512 | 0.82 | KMT2A (0.42) | HTTALDH1A1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL17366373 | 0.81 | ALDH1A1 (0.40) | HTTALDH1A1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL17366377 | 0.81 | HPGD (0.35) | HTTALDH1A1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL17366360 | 0.80 | MAOB (0.45) | HTTALDH1A1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL21208372 | 0.80 | KMT2A (0.40) | HTTALDH1A1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL17366378 | 0.78 | MAPT (0.40) | HTTALDH1A1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL17367920 | 0.78 | ALDH1A1 (0.54) | HTTALDH1A1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL7890806 | 0.76 | ALDH1A1 (0.38) | HTTALDH1A1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL7891040 | 0.76 | ALDH1A1 (0.43) | ALDH1A1CYP3A4RELAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2960229-B1 | HYDRAZONE DERIVATIVE OF TRIPHENYLAMINE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | KYOCERA DOCUMENT SOLUTIONS INC (JP) | 2017-02-15 | — | — | EP | disclosed |
| US-9454091-B2 | Hydrazone derivative of triphenylamine and electrophotographic photosensitive member | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2016-09-27 | — | — | US | disclosed |
| US-9454091-B2 | Hydrazone derivative of triphenylamine and electrophotographic photosensitive member | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2016-09-27 | — | — | US | disclosed |
| US-20150378269-A1 | HYDRAZONE DERIVATIVE OF TRIPHENYLAMINE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2015-12-31 | — | — | US | disclosed |
| US-20150378269-A1 | HYDRAZONE DERIVATIVE OF TRIPHENYLAMINE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2015-12-31 | — | — | US | disclosed |
| EP-2960229-A1 | HYDRAZONE DERIVATIVE OF TRIPHENYLAMINE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | Kyocera Document Solutions Inc. (JP) | 2015-12-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150378269-A1 | HYDRAZONE DERIVATIVE OF TRIPHENYLAMINE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | NAT1, GSTA1, PKN1 | HTT 223/4885ALDH1A1 49/4885CYP1A2 250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.