Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16273332 | 0.85 | RELA (0.49) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL17366379 | 0.84 | RELA (0.54) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL16604904 | 0.80 | MAPT (0.40) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL17366377 | 0.79 | HPGD (0.35) | MAPTKMT2AALDH1A1MEN1TDP1 | |
| SCHEMBL17366361 | 0.78 | HTT (0.36) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL17366360 | 0.78 | MAOB (0.45) | MAPTKMT2AALDH1A1MEN1TDP1 | |
| SCHEMBL7893720 | 0.77 | ALDH1A1 (0.48) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL19872214 | 0.77 | EGFR (0.44) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL7895373 | 0.77 | ALDH1A1 (0.45) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL17366373 | 0.75 | ALDH1A1 (0.40) | MAPTKMT2AALDH1A1MEN1RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2960229-B1 | HYDRAZONE DERIVATIVE OF TRIPHENYLAMINE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | KYOCERA DOCUMENT SOLUTIONS INC (JP) | 2017-02-15 | — | — | EP | disclosed |
| US-9454091-B2 | Hydrazone derivative of triphenylamine and electrophotographic photosensitive member | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2016-09-27 | — | — | US | disclosed |
| US-9454091-B2 | Hydrazone derivative of triphenylamine and electrophotographic photosensitive member | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2016-09-27 | — | — | US | disclosed |
| US-20150378269-A1 | HYDRAZONE DERIVATIVE OF TRIPHENYLAMINE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2015-12-31 | — | — | US | disclosed |
| US-20150378269-A1 | HYDRAZONE DERIVATIVE OF TRIPHENYLAMINE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2015-12-31 | — | — | US | disclosed |
| EP-2960229-A1 | HYDRAZONE DERIVATIVE OF TRIPHENYLAMINE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | Kyocera Document Solutions Inc. (JP) | 2015-12-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150378269-A1 | HYDRAZONE DERIVATIVE OF TRIPHENYLAMINE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | NAT1, GSTA1, PKN1 | MAPT 3553/4885NPC1 1130/4885RAB9A 3384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.