Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | INSR | P06213 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13291600 | 0.84 | MAOB (0.42) | ALDH1A1HTTTRPM8NFE2L2MAPT | |
| SCHEMBL13304637 | 0.84 | MAOB (0.42) | ALDH1A1HTTTRPM8NFE2L2MAPT | |
| SCHEMBL13010108 | 0.84 | RELA (0.44) | ALDH1A1TRPM8MEN1KMT2ANFE2L2 | |
| SCHEMBL14445153 | 0.84 | RELA (0.44) | ALDH1A1TRPM8MEN1KMT2ANFE2L2 | |
| SCHEMBL4400822 | 0.84 | RELA (0.44) | ALDH1A1TRPM8MEN1KMT2ANFE2L2 | |
| SCHEMBL18993254 | 0.83 | NFE2L2 (0.41) | ALDH1A1HTTCYP3A4TRPM8MEN1 | |
| SCHEMBL15759517 | 0.83 | APP (0.42) | ALDH1A1HTTTRPM8NFE2L2MAPT | |
| SCHEMBL17367920 | 0.83 | ALDH1A1 (0.54) | ALDH1A1HTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10938508 | 0.82 | KMT2A (0.44) | ALDH1A1HTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12677645 | 0.82 | KMT2A (0.44) | ALDH1A1HTTCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2960229-B1 | HYDRAZONE DERIVATIVE OF TRIPHENYLAMINE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | KYOCERA DOCUMENT SOLUTIONS INC (JP) | 2017-02-15 | — | — | EP | disclosed |
| US-9454091-B2 | Hydrazone derivative of triphenylamine and electrophotographic photosensitive member | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2016-09-27 | — | — | US | disclosed |
| US-9454091-B2 | Hydrazone derivative of triphenylamine and electrophotographic photosensitive member | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2016-09-27 | — | — | US | disclosed |
| US-20150378269-A1 | HYDRAZONE DERIVATIVE OF TRIPHENYLAMINE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2015-12-31 | — | — | US | disclosed |
| US-20150378269-A1 | HYDRAZONE DERIVATIVE OF TRIPHENYLAMINE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2015-12-31 | — | — | US | disclosed |
| EP-2960229-A1 | HYDRAZONE DERIVATIVE OF TRIPHENYLAMINE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | Kyocera Document Solutions Inc. (JP) | 2015-12-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150378269-A1 | HYDRAZONE DERIVATIVE OF TRIPHENYLAMINE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | NAT1, GSTA1, PKN1 | ALDH1A1 49/4885HTT 223/4885CYP1A2 250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.