SCHEMBL17366452

SCHEMBL17366452

CN(CO)CN(CNc1ccc(Cc2ccc(N(C(C)(C)C)C(C)(C)C)cc2)cc1)c1ccc(Cc2ccc(N(C(C)(C)C)C(C)(C)C)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CNR2 P34972 1/20 0.32
POLB P06746 1/20 0.32
HDAC1 Q13547 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17693520 0.90 CNR2 (0.33) ALDH1A1CYP3A4TSHRMAPK1TDP1
SCHEMBL17933705 0.82 CNR2 (0.30) CNR2
SCHEMBL18590807 0.82 CNR2 (0.30) CNR2
SCHEMBL17343555 0.69 MAPT (0.42) ALDH1A1TSHRMAPK1TDP1HDAC1
SCHEMBL17348254 0.69 CNR2 (0.33) ALDH1A1CYP3A4MAPK1CNR2POLB
SCHEMBL19002876 0.66 MAPT (0.42) ALDH1A1TSHRMAPK1TDP1POLB
SCHEMBL17634991 0.64 ALDH1A1 (0.39) ALDH1A1CYP3A4TSHRMAPK1TDP1
SCHEMBL19646065 0.62 APP (0.46) ALDH1A1
SCHEMBL11529043 0.61 LOXL2 (0.45) ALDH1A1CYP3A4TSHRMAPK1TDP1
SCHEMBL2759019 0.61 ALDH1A1 (0.47) ALDH1A1CYP3A4TSHRMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170130024-A1 HIGH-PERFORMANCE, FILLER-REINFORCED, RECYCLABLE COMPOSITE MATERIALS INTERNATIONAL BUSINESS MACHINES CORPORATION 2017-05-11 US disclosed
US-9598284-B2 High-performance, filler-reinforced, recyclable composite materials INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2017-03-21 US disclosed
US-9598608-B2 Soluble, processable polyhemiaminals and polyhexahydrotriazines INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2017-03-21 US disclosed
US-9586824-B2 High-performance, filler-reinforced, recyclable composite materials INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2017-03-07 US disclosed
US-20160304348-A1 HIGH-PERFORMANCE, FILLER-REINFORCED, RECYCLABLE COMPOSITE MATERIALS INTERNATIONAL BUSINESS MACHINES 2016-10-20 US disclosed
US-20160194472-A1 HIGH-PERFORMANCE, FILLER-REINFORCED, RECYCLABLE COMPOSITE MATERIALS INTERNATIONAL BUSINESS MACHINES CORPORATION 2016-07-07 US disclosed
US-20160039966-A1 HIGH-PERFORMANCE, FILLER-REINFORCED, RECYCLABLE COMPOSITE MATERIALS INTERNATIONAL BUSINESS MACHINES CORPORATION 2016-02-11 US disclosed
US-20150376442-A1 SOLUBLE, PROCESSABLE POLYHEMIAMINALS AND POLYHEXAHYDROTRIAZINES INTERNATIONAL BUSINESS MACHINES CORPORATION 2015-12-31 US disclosed