SCHEMBL1736740

SCHEMBL1736740

C=CC(=O)OCNC(=O)Nc1ccc(O)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
MTOR P42345 1/20 0.43
MAPT P10636 5/20 0.41
THRB P10828 4/20 0.41
GAA P10253 4/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
RECQL P46063 2/20 0.41
KDM4E B2RXH2 1/20 0.41
TP53 P04637 1/20 0.41
PLEC Q15149 1/20 0.41
ALDH1A1 P00352 3/20 0.40
CYP1A1 P04798 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
PEPD P12955 1/20 0.40
CA12 O43570 1/20 0.40
BRD4 O60885 1/20 0.40
NR1I2 O75469 1/20 0.40
CA1 P00915 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1735862 0.85 RAB9A (0.47) MAOAMAOBMTORMAPTTHRB
SCHEMBL3250905 0.83 ALDH1A1 (0.45) MTORMAPTALDH1A1MEN1KMT2A
SCHEMBL1735654 0.82 ALDH1A1 (0.46) MAOAMAOBKDM4EALDH1A1KMT2A
SCHEMBL3251083 0.81 ALDH1A1 (0.47) MAPTGAARECQLALDH1A1MEN1
SCHEMBL1735986 0.78 MAPT (0.46) MAOAMAOBMTORMAPTTHRB
SCHEMBL8937595 0.77 MAOA (0.53) MAOAMAOBMTORMAPTTHRB
SCHEMBL1735947 0.77 GAA (0.43) MAPTTHRBGAAKDM4ETP53
SCHEMBL28804177 0.76 MAOA (0.53) MAOAMAOBMAPTTHRBGAA
SCHEMBL14012044 0.76 MAOA (0.52) MAOAMAOBMTORMAPTTHRB
SCHEMBL3251658 0.75 TRPV1 (0.46) GAAKDM4EALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3521927-B1 POSITIVE WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD FOR MANUFACTURING THE PRECURSOR AND METHOD FOR PRODUCING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORP (JP) 2021-10-27 EP disclosed
US-10649337-B2 Positive type lithographic printing plate precursor, method of producing same, and method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2020-05-12 US disclosed
EP-3521927-A1 POSITIVE PLANOGRAPHIC PRINTING ORIGINAL PLATE AND METHOD FOR MANUFACTURING SAME, AND METHOD FOR PRODUCING PLANOGRAPHIC PRINTING PLATE FUJIFILM Corporation (JP) 2019-08-07 EP disclosed
US-20190212652-A1 POSITIVE TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PRODUCING SAME, AND METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2019-07-11 US disclosed
EP-2538275-B1 PROCESS FOR MAKING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORP (JP) 2014-10-29 EP disclosed
US-20130004897-A1 METHOD FOR MANUFACTURING A PLANOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2013-01-03 US disclosed
EP-2538275-A1 PROCESS FOR MAKING LITHOGRAPHIC PRINTING PLATE FUJIFILM Corporation (JP) 2012-12-26 EP disclosed
EP-2251195-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2011-11-16 EP disclosed
US-20110265148-A1 SYSTEM AND METHOD FOR CREATING A SECURE TRUSTED SOCIAL NETWORK TAM CHUNG MING 2011-10-27 US disclosed
EP-2251195-A1 Lithographic printing plate precursor Fujifilm Corporation (JP) 2010-11-17 EP disclosed
EP-1136886-B1 Positive-working presensitized plate useful for preparing a lithographic printing plate FUJIFILM CORP (JP) 2010-05-19 EP disclosed
US-20090246693-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20080182202-A1 Planographic printing plate material and resin used therein KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-31 US disclosed
EP-0737896-B1 Photosensitive composition and photosensitive planographic printing plate KODAK POLYCHROME GRAPHICS JP (JP) 2003-08-27 EP disclosed
US-6517987-B2 Mixture of 1,2-naphthoquinone-2-diazide-5-sulfonic acid and polymer FUJI PHOTO FILM CO., LTD. (JP) 2003-02-11 US disclosed
US-20010041299-A1 Positive-working presensitized plate useful for preparing a lithographic printing plate FUJIFILM CORPORATION (JP) 2001-11-15 US disclosed
EP-1136886-A1 Positive-working presensitized plate useful for preparing a lithographic printing plate Fuji Photo Film Co., Ltd. (JP) 2001-09-26 EP disclosed
US-5731127-A WEAR RESISTANCE, SOLVENT RESISTANCE DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-03-24 US disclosed
EP-0737896-A2 Photosensitive composition and photosensitive planographic printing plate DAINIPPON INK AND CHEMICALS, INC. (JP) 1996-10-16 EP disclosed