SCHEMBL17368998

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17369001	0.98	ESR1 (0.46)	ESR1ESR2MAPK10GRIA1CACNG8
	SCHEMBL26344695	0.98	ESR1 (0.50)	ESR1ESR2MAPK10GRIA1CACNG8
	SCHEMBL26345386	0.98	ESR1 (0.50)	ESR1ESR2MAPK10GRIA1CACNG8
	SCHEMBL10353261	0.98	ESR1 (0.50)	ESR1ESR2MAPK10GRIA1CACNG8
	SCHEMBL26345383	0.97	ESR1 (0.47)	ESR1ESR2MAPK10GRIA1CACNG8
	SCHEMBL25668147	0.97	ESR1 (0.52)	ESR1ESR2MAPK10GRIA1CACNG8
	SCHEMBL17932821	0.97	ESR1 (0.52)	ESR1ESR2MAPK10GRIA1CACNG8
	SCHEMBL20906742	0.97	ESR1 (0.52)	ESR1ESR2MAPK10GRIA1CACNG8
	SCHEMBL23784966	0.97	MAPK10 (0.45)	ESR1ESR2MAPK10GRIA1CACNG8
	SCHEMBL12571637	0.96	ESR1 (0.53)	ESR1ESR2MAPK10GRIA1CACNG8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.