Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | BUB1 | O43683 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18803284 | 0.87 | NLRP3 (0.35) | RAB9AFFAR3TSHRL3MBTL1KDM4E | |
| SCHEMBL17378363 | 0.79 | KEAP1 (0.43) | TP53RAB9APTGS2ALDH1A1 | |
| SCHEMBL10897374 | 0.76 | TP53 (0.41) | TP53RAB9AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL17378352 | 0.76 | KEAP1 (0.43) | TP53RAB9APTGS2ALDH1A1 | |
| SCHEMBL17378360 | 0.75 | KEAP1 (0.42) | TP53RAB9APOLBALDH1A1 | |
| SCHEMBL17378351 | 0.75 | KEAP1 (0.42) | TP53RAB9APOLBALDH1A1 | |
| SCHEMBL17378357 | 0.75 | KEAP1 (0.42) | TP53RAB9APOLBALDH1A1 | |
| SCHEMBL2597419 | 0.73 | SLC6A3 (0.40) | TP53RAB9AKDM4EALDH1A1 | |
| SCHEMBL17378348 | 0.73 | KEAP1 (0.39) | — | |
| SCHEMBL17378346 | 0.73 | KEAP1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3164196-B1 | TOPICAL FORMULATIONS FOR UV PROTECTION | TOPGENIX INC (US) | 2021-08-18 | — | — | EP | disclosed |
| US-10064797-B2 | Topical formulations for UV protection | TopGeniX, Inc. (US) | 2018-09-04 | — | — | US | disclosed |
| EP-3164196-A1 | TOPICAL FORMULATIONS FOR UV PROTECTION | TOPGENIX, INC. (US) | 2017-05-10 | — | — | EP | disclosed |
| US-20170119641-A1 | TOPICAL FORMULATIONS FOR UV PROTECTION | TopGeniX, Inc. | 2017-05-04 | — | — | US | disclosed |
| US-20170119641-A1 | TOPICAL FORMULATIONS FOR UV PROTECTION | TopGeniX, Inc. | 2017-05-04 | — | — | US | disclosed |
| US-20170119641-A1 | TOPICAL FORMULATIONS FOR UV PROTECTION | TopGeniX, Inc. | 2017-05-04 | — | — | US | disclosed |
| WO-2015195546-A1 | TOPICAL FORMULATIONS FOR UV PROTECTION | TopGeniX, Inc. (US) | 2015-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10064797-B2 | Topical formulations for UV protection | ERCC4, ERCC1, UNG | TP53 612/4885RAB9A 1217/4885FFAR3 3490/4885 |
| US-20170119641-A1 | TOPICAL FORMULATIONS FOR UV PROTECTION | ERCC4, ERCC1, UNG | TP53 612/4885RAB9A 1217/4885FFAR3 3490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.