Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | VCP | P55072 | 2/20 | 0.48 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.48 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.48 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26095552 | 0.78 | NR1H4 (0.70) | MAPTMEN1KMT2ANOTUMNR1H4 | |
| SCHEMBL19075472 | 0.76 | RAB9A (0.51) | MAPTMEN1KMT2ACYP3A4TSHR | |
| SCHEMBL17377369 | 0.73 | VCP (0.55) | MAPTALOX5VCPMAPKAPK2MEN1 | |
| SCHEMBL11080475 | 0.73 | MEN1 (0.53) | MAPTMEN1KMT2ACYP3A4GAA | |
| SCHEMBL3532271 | 0.72 | SPHK2 (0.74) | VCPMEN1KMT2AMAPK1SPHK2 | |
| SCHEMBL20968220 | 0.72 | NR1H4 (0.59) | MAPTMEN1KMT2ACYP3A4MAPK1 | |
| SCHEMBL17377392 | 0.72 | SPHK2 (0.74) | VCPMEN1KMT2AMAPK1SPHK2 | |
| SCHEMBL4416547 | 0.71 | CASP3 (0.62) | MAPTMEN1KMT2AGAANPC1 | |
| SCHEMBL11156115 | 0.71 | GSK3B (0.53) | MAPTALOX5VCPMAPKAPK2MEN1 | |
| SCHEMBL27643199 | 0.71 | PIK3CA (0.74) | MAPTALOX5VCPMAPKAPK2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828351-B2 | Enzyme interacting agents | MONASH UNIVERSITY (AU) | 2017-11-28 | — | — | US | disclosed |
| US-9828351-B2 | Enzyme interacting agents | MONASH UNIVERSITY (AU) | 2017-11-28 | — | — | US | disclosed |
| US-20170190698-A1 | ENZYME INTERACTING AGENTS | CENTRAL ADELAIDE LOCAL HEALTH NETWORK INCORPORATED (AU) | 2017-07-06 | — | — | US | disclosed |
| US-20170190698-A1 | ENZYME INTERACTING AGENTS | CENTRAL ADELAIDE LOCAL HEALTH NETWORK INCORPORATED (AU) | 2017-07-06 | — | — | US | disclosed |
| US-20170190698-A1 | ENZYME INTERACTING AGENTS | CENTRAL ADELAIDE LOCAL HEALTH NETWORK INCORPORATED (AU) | 2017-07-06 | — | — | US | disclosed |
| EP-3160949-A1 | ENZYME INTERACTING AGENTS | Monash University (AU) | 2017-05-03 | — | — | EP | disclosed |
| WO-2015196258-A1 | ENZYME INTERACTING AGENTS | MONASH UNIVERSITY (AU) | 2015-12-30 | — | — | WO | disclosed |
| WO-2015196258-A1 | ENZYME INTERACTING AGENTS | MONASH UNIVERSITY (AU) | 2015-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190698-A1 | ENZYME INTERACTING AGENTS | SMPD1, SMPD2, ASAH1 | MAPT 3836/4885ALOX5 466/4885VCP 988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.