Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.45 |
| ▸ | STK17A | Q9UEE5 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11089778 | 0.81 | SMN1; SMN2 (0.53) | MEN1KMT2AGAASCN9ANPC1 | |
| SCHEMBL16014242 | 0.81 | MAPT (0.44) | MEN1KMT2AADORA3SLC6A2PDE4A | |
| SCHEMBL11088916 | 0.81 | RAB9A (0.53) | MEN1KMT2AGAASCN9ANPC1 | |
| SCHEMBL17403482 | 0.81 | MAPT (0.52) | MEN1KMT2AGAAGFERNPC1 | |
| SCHEMBL11078558 | 0.81 | POLA1 (0.50) | STK17ASTK17BTDO2NPY5R | |
| SCHEMBL11079956 | 0.77 | POLB (0.43) | MEN1KMT2AADORA3SLC6A2PDE4A | |
| SCHEMBL11630110 | 0.75 | KCNH3 (0.59) | MEN1KMT2AADORA3SLC6A2PDE4A | |
| SCHEMBL2452956 | 0.75 | ADORA3 (0.68) | MEN1KMT2AADORA3SLC6A2PDE4A | |
| SCHEMBL11083592 | 0.73 | HDAC3 (0.40) | MEN1KMT2AGAAMAPTCYP3A4 | |
| SCHEMBL17377367 | 0.73 | MAPT (0.48) | MEN1KMT2AGAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4446142-A | HYPOTENSIVE AGENTS | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1984-05-01 | — | — | US | claimed |
| EP-0044266-A2 | Substituted 3,5-diamino-1,2,4-oxadiazoles and 3,5-diamino-1,2,4-thiadiazoles, their preparation and pharmaceutical compositions containing them | Beiersdorf Aktiengesellschaft (DE) | 1982-01-20 | — | — | EP | claimed |
| US-4446142-A | HYPOTENSIVE AGENTS | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1984-05-01 | — | — | US | disclosed |
| EP-0044266-A2 | Substituted 3,5-diamino-1,2,4-oxadiazoles and 3,5-diamino-1,2,4-thiadiazoles, their preparation and pharmaceutical compositions containing them | Beiersdorf Aktiengesellschaft (DE) | 1982-01-20 | — | — | EP | disclosed |
| EP-0044266-A2 | Substituted 3,5-diamino-1,2,4-oxadiazoles and 3,5-diamino-1,2,4-thiadiazoles, their preparation and pharmaceutical compositions containing them | Beiersdorf Aktiengesellschaft (DE) | 1982-01-20 | — | — | EP | disclosed |