Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1737992 | 0.93 | FABP4 (0.43) | MAPTFABP4L3MBTL1MAOBHTR6 | |
| SCHEMBL1737397 | 0.90 | FABP4 (0.41) | MAPTFABP4ALDH1A1TSHRHPGD | |
| SCHEMBL1737494 | 0.89 | ALDH1A1 (0.41) | MAPTFABP4ALDH1A1TSHRHPGD | |
| SCHEMBL1738202 | 0.89 | ALDH1A1 (0.45) | MAPTFABP4MAOBHTR6PLA2G2A | |
| SCHEMBL1736324 | 0.89 | PLA2G2A (0.38) | MAPTFABP4PLA2G2AALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL1739172 | 0.88 | ALDH1A1 (0.40) | MAPTFABP4ALDH1A1TSHRHPGD | |
| SCHEMBL1739793 | 0.88 | LMNA (0.45) | MAPTL3MBTL1ALDH1A1TSHRHPGD | |
| SCHEMBL1737743 | 0.88 | MAOB (0.39) | MAPTFABP4L3MBTL1MAOBHTR6 | |
| SCHEMBL1737472 | 0.88 | TMEM97 (0.42) | MAPTFABP4HTR6ALDH1A1TSHR | |
| SCHEMBL1737791 | 0.88 | GRIN2D (0.41) | MAPTMAOBHTR6PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |
| US-7662832-B2 | Pyrrolo[2,3-c]pyridine derivatives and processes for the preparation thereof | YUHAN CORPORATION (KR) | 2010-02-16 | — | — | US | claimed |
| US-20070219230-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2007-09-20 | — | — | US | claimed |
| US-8188114-B2 | Pyrrolo[2,3-C]pyridine derivatives and processes for the preparation thereof | YUHAN CORPORATION (KR) | 2012-05-29 | — | — | US | disclosed |
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | disclosed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | disclosed |
| US-20100069430-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2010-03-18 | — | — | US | disclosed |
| US-7662832-B2 | Pyrrolo[2,3-c]pyridine derivatives and processes for the preparation thereof | YUHAN CORPORATION (KR) | 2010-02-16 | — | — | US | disclosed |
| EP-1784404-A4 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2009-09-09 | — | — | EP | disclosed |
| US-20070219230-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2007-09-20 | — | — | US | disclosed |
| EP-1784404-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006025716-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069430-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | PGA5, ATP6AP1, ATP6V1H | MAPT 3920/4885FABP4 4680/4885L3MBTL1 4876/4885 |
| US-20070219230-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | PGA5, ATP6AP1, ATP6V1H | MAPT 3920/4885FABP4 4680/4885L3MBTL1 4876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.