Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.71 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.71 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.71 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.71 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.71 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.71 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.71 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.71 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.71 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.68 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | MMP13 | P45452 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18063501 | 0.79 | HPGD (0.73) | HDAC6SCN9ALMNAMMP13HPGD | |
| SCHEMBL9692595 | 0.73 | SMN1; SMN2 (0.54) | HDAC6HDAC4HDAC7HDAC9HDAC5 | |
| SCHEMBL17383001 | 0.72 | ALDH1A1 (1.00) | HDAC6HDAC4HDAC7HDAC9HDAC5 | |
| SCHEMBL17382993 | 0.71 | HDAC6 (0.79) | HDAC6HDAC4HDAC7HDAC9HDAC5 | |
| SCHEMBL16910497 | 0.71 | HPGD (0.73) | LMNAMMP13HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL6841501 | 0.71 | PARP1 (0.62) | ALDH1A1MAPTKMT2A | |
| SCHEMBL6836782 | 0.70 | RAB9A (0.48) | LMNAHPGDALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9870231 | 0.69 | LMNA (0.57) | ESR2LMNAMMP13HPGDALDH1A1 | |
| SCHEMBL1890037 | 0.69 | GPR84 (0.67) | HDAC6HDAC5HDAC3HDAC1HDAC2 | |
| SCHEMBL17382811 | 0.68 | HDAC6 (0.61) | HDAC6HDAC4HDAC7HDAC9HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981920-B2 | Inhibitors of histone deacetylase | RODIN THERAPEUTICS, INC. (US) | 2018-05-29 | — | — | US | disclosed |
| US-20170204070-A1 | INHIBITORS OF HISTONE DEACETYLASE | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2017-07-20 | — | — | US | disclosed |
| WO-2015200619-A1 | INHIBITORS OF HISTONE DEACETYLASE | RODIN THERAPEUTICS, INC. (US) | 2015-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170204070-A1 | INHIBITORS OF HISTONE DEACETYLASE | HDAC2, HDAC1, HDAC5 | HDAC6 4/4885HDAC4 6/4885HDAC7 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.