Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1738285 | 0.76 | ACHE (0.44) | LMNACYP2A6MAPTRAB9ANPSR1 | |
| SCHEMBL3392085 | 0.74 | LMNA (0.42) | LMNACYP2A6MAPTRAB9ANPSR1 | |
| SCHEMBL1739587 | 0.74 | ACHE (0.39) | MAPTHTTMEN1KMT2AMAOA | |
| SCHEMBL1739837 | 0.74 | CYP2A6 (0.42) | LMNACYP2A6MAPTRAB9ANPSR1 | |
| SCHEMBL1739829 | 0.73 | MEN1 (0.38) | LMNACYP2A6MAPTRAB9ANPSR1 | |
| SCHEMBL95991 | 0.72 | — | — | |
| SCHEMBL9695604 | 0.72 | RHEB (0.41) | LMNAMEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL1738328 | 0.70 | CA1 (0.52) | LMNACYP2A6MAPTRAB9ANPSR1 | |
| SCHEMBL31464838 | 0.70 | MAPT (0.42) | LMNACYP2A6MAPTRAB9ANPSR1 | |
| SCHEMBL96393 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879567-A1 | AMINO ACID DERIVATIVES | Pfizer Limited (GB) | 2008-01-23 | — | — | EP | claimed |
| US-20060247291-A1 | Amino acid derivatives | PFIZER, INC. | 2006-11-02 | — | — | US | claimed |
| WO-2006114707-A1 | AMINO ACID DERIVATIVES | PFIZER LIMITED (GB) | 2006-11-02 | — | — | WO | claimed |
| US-8669025-B2 | Polymerizable composition, cured film, color filter, method of producing color filter and solid-state image sensor | FUJIFILM CORPORATION (JP) | 2014-03-11 | — | — | US | disclosed |
| EP-2390272-A1 | Polymerizable composition, cured film, color filter, method of producing color filter and solid-state image sensor | FUJIFILM Corporation (JP) | 2011-11-30 | — | — | EP | disclosed |
| US-20110255570-A1 | ADAPTIVE FREQUENCY HOPPING IN TIME-SLOTTED BASED WIRELESS NETWORK | HITACHI, LTD. (JP) | 2011-10-20 | — | — | US | disclosed |
| US-7612226-B2 | Amino acid derivatives | PFIZER INC. (US) | 2009-11-03 | — | — | US | disclosed |
| EP-1879567-A1 | AMINO ACID DERIVATIVES | Pfizer Limited (GB) | 2008-01-23 | — | — | EP | disclosed |
| US-20060247291-A1 | Amino acid derivatives | PFIZER, INC. | 2006-11-02 | — | — | US | disclosed |
| WO-2006114707-A1 | AMINO ACID DERIVATIVES | PFIZER LIMITED (GB) | 2006-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247291-A1 | Amino acid derivatives | OPRL1, BCAT2, BCAT1 | LMNA 4367/4885CYP2A6 2245/4885MAPT 2377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.