Hydrochloric Acid

Hydrochloric Acid

SCHEMBL8973398

C=CC(=O)NCC[N+](C)(C)CCCC.[Cl-]

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.59
ZDHHC2 Q9UIJ5 1/20 0.59
KMT2A Q03164 2/20 0.42
ATM Q13315 1/20 0.42
DNM1 Q05193 5/20 0.39
TSHR P16473 2/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CBLB Q13191 2/20 0.37
HTT P42858 1/20 0.36
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
POLB P06746 1/20 0.35
GRK2 P25098 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
GAA P10253 1/20 0.35
THRA P10827 1/20 0.34
THRB P10828 1/20 0.34
TGM2 P21980 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15830116 0.98 ZDHHC20 (0.61) ZDHHC20ZDHHC2KMT2AATMDNM1
Hydrochloric Acid SCHEMBL29634898 0.94 ZDHHC20 (0.65) ZDHHC20ZDHHC2KMT2AATMDNM1
SCHEMBL19894632 0.92 ZDHHC20 (0.67) ZDHHC20ZDHHC2KMT2AATMDNM1
SCHEMBL15830115 0.92 ZDHHC20 (0.66) ZDHHC20ZDHHC2KMT2AATMDNM1
Bromide SCHEMBL29148564 0.90 ZDHHC20 (0.65) ZDHHC20ZDHHC2KMT2AATMDNM1
Bromide SCHEMBL31633221 0.90 ZDHHC20 (0.65) ZDHHC20ZDHHC2KMT2AATMDNM1
Bromide SCHEMBL28162997 0.90 ZDHHC20 (0.65) ZDHHC20ZDHHC2KMT2AATMDNM1
Bromide SCHEMBL278071 0.90 ZDHHC20 (0.65) ZDHHC20ZDHHC2KMT2AATMDNM1
Bromide SCHEMBL31456600 0.90 ZDHHC20 (0.64) ZDHHC20ZDHHC2KMT2AATMDNM1
Hydrochloric Acid SCHEMBL2551112 0.90 ZDHHC20 (0.53) ZDHHC20ZDHHC2KMT2AATMDNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0191980-B1 POLYMERS FOR USE AS FILTRATION CONTROL AIDS IN DRILLING MUDS CALGON CORPORATION (US) 1990-05-09 EP claimed
EP-0191980-A2 Polymers for use as filtration control aids in drilling muds CALGON CORPORATION (US) 1986-08-27 EP claimed
EP-3347446-B1 A STABLE LAUNDRY OR CLEANING COMPOSITION, PROCESS FOR PREPARING THE SAME, AND METHOD OF USE ISP INVESTMENTS LLC (US) 2024-12-11 EP disclosed
US-20240375983-A1 SCALE INHIBITOR METHODS AND COMPOSITIONS IN SEVERE OPERATING CONDITIONS CHAMPIONX LLC 2024-11-14 US disclosed
EP-4341359-A1 SCALE INHIBITOR METHODS AND COMPOSITIONS IN SEVERE OPERATING CONDITIONS ChampionX LLC (US) 2024-03-27 EP disclosed
WO-2023288093-A1 SCALE INHIBITOR METHODS AND COMPOSITIONS IN SEVERE OPERATING CONDITIONS CHAMPIONX USA INC. (US) 2023-01-19 WO disclosed
US-11384316-B2 Stable laundry cleaning composition and method comprising a polyAPTAC-containing polymer ISP INVESTMENTS LLC (US) 2022-07-12 US disclosed
US-20200224128-A1 A STABLE LAUNDRY OR CLEANING COMPOSITION, PROCESS FOR PREPARING THE SAME, AND METHOD OF USE ISP INVESTMENTS LLC (US) 2020-07-16 US disclosed
EP-3347446-A1 A STABLE LAUNDRY OR CLEANING COMPOSITION, PROCESS FOR PREPARING THE SAME, AND METHOD OF USE ISP Investments LLC (US) 2018-07-18 EP disclosed
WO-2017044749-A1 A STABLE LAUNDRY OR CLEANING COMPOSITION, PROCESS FOR PREPARING THE SAME, AND METHOD OF USE ISP INVESTMENTS LLC (US) 2017-03-16 WO disclosed
EP-0702734-A1 IMPROVED METHOD OF REMOVING HYDROPHILIC INK HIGH POINT CHEMICAL CORPORATION (US) 1996-03-27 EP disclosed
US-5415733-A Water soluble cationic polymer HIGH POINT CHEMICAL CORP. (US) 1995-05-16 US disclosed
WO-1994028237-A1 IMPROVED METHOD OF REMOVING HYDROPHILIC INK HIGH POINT CHEMICAL CORPORATION (US) 1994-12-08 WO disclosed
EP-0191980-B1 POLYMERS FOR USE AS FILTRATION CONTROL AIDS IN DRILLING MUDS CALGON CORPORATION (US) 1990-05-09 EP disclosed
EP-0191980-A2 Polymers for use as filtration control aids in drilling muds CALGON CORPORATION (US) 1986-08-27 EP disclosed