Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.53 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CBLB | Q13191 | 2/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3901312 | 0.90 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL8973398 | 0.90 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL15830116 | 0.88 | ZDHHC20 (0.61) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL2586583 | 0.88 | ZDHHC20 (0.61) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL17414844 | 0.87 | ZDHHC20 (0.50) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL29634898 | 0.87 | ZDHHC20 (0.65) | ZDHHC20ZDHHC2KMT2AATMCBLB | |
| SCHEMBL3764640 | 0.85 | ZDHHC20 (0.52) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL17322450 | 0.85 | ZDHHC20 (0.52) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL16798897 | 0.85 | ZDHHC20 (0.67) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL19894632 | 0.85 | ZDHHC20 (0.67) | ZDHHC20ZDHHC2KMT2AATMDNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190040172-A1 | AQUEOUS EMULSION POLYMERS AS RHEOLOGY MODIFIERS, COMPOSITIONS THEREOF, AND METHOD OF USE | ISP INVESTMENTS LLC (US) | 2019-02-07 | — | — | US | claimed |
| EP-3411418-A1 | AQUEOUS EMULSION POLYMERS AS RHEOLOGY MODIFIERS, COMPOSITIONS THEREOF, AND METHOD OF USE | ISP Investments LLC (US) | 2018-12-12 | — | — | EP | claimed |
| WO-2017136800-A1 | AQUEOUS EMULSION POLYMERS AS RHEOLOGY MODIFIERS, COMPOSITIONS THEREOF, AND METHOD OF USE | ISP INVESTMENTS LLC (US) | 2017-08-10 | — | — | WO | claimed |
| EP-0191980-B1 | POLYMERS FOR USE AS FILTRATION CONTROL AIDS IN DRILLING MUDS | CALGON CORPORATION (US) | 1990-05-09 | — | — | EP | claimed |
| EP-0191980-A2 | Polymers for use as filtration control aids in drilling muds | CALGON CORPORATION (US) | 1986-08-27 | — | — | EP | claimed |
| EP-3347446-B1 | A STABLE LAUNDRY OR CLEANING COMPOSITION, PROCESS FOR PREPARING THE SAME, AND METHOD OF USE | ISP INVESTMENTS LLC (US) | 2024-12-11 | — | — | EP | disclosed |
| US-11384316-B2 | Stable laundry cleaning composition and method comprising a polyAPTAC-containing polymer | ISP INVESTMENTS LLC (US) | 2022-07-12 | — | — | US | disclosed |
| US-10722447-B2 | Sprayable composition comprising high molecular weight charged polymer | ISP INVESTMENTS LLC (US) | 2020-07-28 | — | — | US | disclosed |
| US-20200224128-A1 | A STABLE LAUNDRY OR CLEANING COMPOSITION, PROCESS FOR PREPARING THE SAME, AND METHOD OF USE | ISP INVESTMENTS LLC (US) | 2020-07-16 | — | — | US | disclosed |
| US-20190040172-A1 | AQUEOUS EMULSION POLYMERS AS RHEOLOGY MODIFIERS, COMPOSITIONS THEREOF, AND METHOD OF USE | ISP INVESTMENTS LLC (US) | 2019-02-07 | — | — | US | disclosed |
| EP-3411418-A1 | AQUEOUS EMULSION POLYMERS AS RHEOLOGY MODIFIERS, COMPOSITIONS THEREOF, AND METHOD OF USE | ISP Investments LLC (US) | 2018-12-12 | — | — | EP | disclosed |
| EP-3347446-A1 | A STABLE LAUNDRY OR CLEANING COMPOSITION, PROCESS FOR PREPARING THE SAME, AND METHOD OF USE | ISP Investments LLC (US) | 2018-07-18 | — | — | EP | disclosed |
| US-20170319460-A1 | SPRAYABLE COMPOSITION COMPRISING HIGH MOLECULAR WEIGHT CHARGED POLYMER | ISP INVESTMENTS LLC (US) | 2017-11-09 | — | — | US | disclosed |
| WO-2017136800-A1 | AQUEOUS EMULSION POLYMERS AS RHEOLOGY MODIFIERS, COMPOSITIONS THEREOF, AND METHOD OF USE | ISP INVESTMENTS LLC (US) | 2017-08-10 | — | — | WO | disclosed |
| WO-2017044749-A1 | A STABLE LAUNDRY OR CLEANING COMPOSITION, PROCESS FOR PREPARING THE SAME, AND METHOD OF USE | ISP INVESTMENTS LLC (US) | 2017-03-16 | — | — | WO | disclosed |
| EP-2555741-A1 | SPRAYABLE COMPOSITION COMPRISING HIGH MOLECULAR WEIGHT CHARGED POLYMER | ISP Investments Inc. (US) | 2013-02-13 | — | — | EP | disclosed |
| WO-2011126978-A1 | SPRAYABLE COMPOSITION COMPRISING HIGH MOLECULAR WEIGHT CHARGED POLYMER | ISP INVESTMENTS INC. (US) | 2011-10-13 | — | — | WO | disclosed |
| EP-0191980-B1 | POLYMERS FOR USE AS FILTRATION CONTROL AIDS IN DRILLING MUDS | CALGON CORPORATION (US) | 1990-05-09 | — | — | EP | disclosed |
| US-4652623-A | Polymers for use as filtration control aids in drilling muds | CALGON CORPORATION (US) | 1987-03-24 | — | — | US | disclosed |
| EP-0191980-A2 | Polymers for use as filtration control aids in drilling muds | CALGON CORPORATION (US) | 1986-08-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190040172-A1 | AQUEOUS EMULSION POLYMERS AS RHEOLOGY MODIFIERS, COMPOSITIONS THEREOF, AND METHOD OF USE | MUC1, ACP1, F12 | ACHE 1959/4885ZDHHC20 1988/4885ZDHHC2 3000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.