SCHEMBL1741597

SCHEMBL1741597

Clc1ccc2oc3ncc(Cl)cc3c2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 7/20 0.52
ALDH1A1 P00352 3/20 0.49
KMT2A Q03164 2/20 0.49
LMNA P02545 1/20 0.49
GPR55 Q9Y2T6 1/20 0.49
IDO1 P14902 1/20 0.43
CDC7 O00311 1/20 0.42
DYRK3 O43781 1/20 0.42
IGF1R P08069 1/20 0.42
PIM1 P11309 1/20 0.42
CLK2 P49760 1/20 0.42
GSK3A P49840 1/20 0.42
GSK3B P49841 1/20 0.42
CSNK2A1 P68400 1/20 0.42
DYRK1A Q13627 1/20 0.42
PKN2 Q16513 1/20 0.42
PIM3 Q86V86 1/20 0.42
CLK4 Q9HAZ1 1/20 0.42
PIM2 Q9P1W9 1/20 0.42
ADCY1 Q08828 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17032389 0.86 MAPT (0.40) AHRALDH1A1KMT2ALMNAGPR55
SCHEMBL15631660 0.84 AHR (0.50) AHRALDH1A1KMT2ALMNAGPR55
SCHEMBL22249800 0.80 EGFR (0.49) AHRALDH1A1KMT2ALMNAGPR55
SCHEMBL24911590 0.80 IDO1 (0.39) AHRIDO1NPC1RAB9AKDM4E
SCHEMBL3666822 0.79 ALDH1A1 (0.51) AHRALDH1A1KMT2ALMNAGPR55
SCHEMBL2282515 0.77 AHR (0.78) AHRALDH1A1KMT2ALMNAGPR55
SCHEMBL21930732 0.76 KMT2A (0.51) AHRALDH1A1KMT2ALMNAGPR55
SCHEMBL29785403 0.76 KMT2A (0.51) AHRALDH1A1KMT2ALMNAGPR55
SCHEMBL25493076 0.74 AHR (0.41) AHRKMT2ALMNAIDO1MEN1
SCHEMBL24268388 0.73 AHR (0.79) AHRALDH1A1KMT2ALMNAGPR55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11279709-B2 Specifically substituted aza-dibenzofurans and aza-dibenzothiophenes for organic electronic devices IDEMITSU KOSAN CO., LTD. (JP) 2022-03-22 US disclosed
CN-113943306-A Azadibenzofurans for electronic applications and electronic devices comprising same UDC 爱尔兰有限责任公司 2022-01-18 CN disclosed
CN-106397453-B New materials with aza-dibenzothiophene or aza-dibenzofuran core for PHOLEDs 通用显示公司 2021-06-18 CN disclosed
EP-3689882-A1 NEW MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED Universal Display Corporation (US) 2020-08-05 EP disclosed
EP-3318566-B1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS UDC IRELAND LTD (IE) 2020-06-24 EP disclosed
EP-3318566-B1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS UDC IRELAND LTD (IE) 2020-06-24 EP disclosed
EP-2703405-B1 NEW MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED UNIVERSAL DISPLAY CORP (US) 2020-04-15 EP disclosed
CN-110785422-A Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device 株式会社半导体能源研究所 2020-02-11 CN disclosed
US-20190248804-A1 SPECIFICALLY SUBSTITUTED AZA-DIBENZOFURANS AND AZA-DIBENZOTHIOPHENES FOR ORGANIC ELECTRONIC DEVICES IDEMITSU KOSAN CO., LTD. (JP) 2019-08-15 US disclosed
US-20190248804-A1 SPECIFICALLY SUBSTITUTED AZA-DIBENZOFURANS AND AZA-DIBENZOTHIOPHENES FOR ORGANIC ELECTRONIC DEVICES IDEMITSU KOSAN CO., LTD. (JP) 2019-08-15 US disclosed
WO-2015014791-A1 BENZIMIDAZOLO[2,1-B][1,3]BENZOTHIAZOLES FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2015-02-05 WO disclosed
WO-2015014791-A1 BENZIMIDAZOLO[2,1-B][1,3]BENZOTHIAZOLES FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2015-02-05 WO disclosed
WO-2014044722-A1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2014-03-27 WO disclosed
WO-2014044722-A1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2014-03-27 WO disclosed
EP-2703405-A2 New materials with aza-dibenzothiophene or aza-dibenzofuran core for pholed Universal Display Corporation (US) 2014-03-05 EP disclosed
US-20130060037-A1 MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED UNIVERSAL DISPLAY CORPORATION (US) 2013-03-07 US disclosed
EP-2387576-A2 NEW MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED Universal Display Corporation (US) 2011-11-23 EP disclosed
US-20100187984-A1 MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED UNIVERSAL DISPLAY CORPORATION (US) 2010-07-29 US disclosed
WO-2010083359-A2 NEW MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED UNIVERSAL DISPLAY CORPORATION (US) 2010-07-22 WO disclosed
US-20100113606-A1 AMINOPROPANOL MODULATORS OF BETA-1 ADRENERGIC RECEPTOR AUSPEX PHARMACEUTICALS, INC. (US) 2010-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190248804-A1 SPECIFICALLY SUBSTITUTED AZA-DIBENZOFURANS AND AZA-DIBENZOTHIOPHENES FOR ORGANIC ELECTRONIC DEVICES CDY1; CDY1B, CDYL, CBX8 AHR 1600/4885ALDH1A1 1323/4885KMT2A 600/4885
US-11279709-B2 Specifically substituted aza-dibenzofurans and aza-dibenzothiophenes for organic electronic devices CDY1; CDY1B, CDYL, CBX8 AHR 1593/4885ALDH1A1 1330/4885KMT2A 609/4885
US-20130060037-A1 MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED DDT, FZD7, BRD7 AHR 1999/4885ALDH1A1 1449/4885KMT2A 816/4885
US-20100187984-A1 MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED DDT, FZD7, BRD7 AHR 1999/4885ALDH1A1 1449/4885KMT2A 816/4885
US-20100113606-A1 AMINOPROPANOL MODULATORS OF BETA-1 ADRENERGIC RECEPTOR ADRB1, ADRB2, ADRB3 AHR 849/4885ALDH1A1 513/4885KMT2A 3587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.