SCHEMBL17416280

SCHEMBL17416280

OB(O)c1cccc2c1sc1c(-c3ccc(-c4ccccc4)cc3)cccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIMK1 P53667 1/20 0.43
ALOX5 P09917 1/20 0.42
MGLL Q99685 2/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
PDCD1 Q15116 1/20 0.37
CD274 Q9NZQ7 1/20 0.37
MCL1 Q07820 1/20 0.34
MAPT P10636 1/20 0.34
PARP14 Q460N5 1/20 0.34
S1PR4 O95977 1/20 0.33
S1PR5 Q9H228 1/20 0.33
F9 P00740 1/20 0.33
CYP17A1 P05093 1/20 0.33
CYP1A2 P05177 1/20 0.33
MEN1 O00255 1/20 0.33
POLB P06746 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29876020 0.97 LIMK1 (0.46) LIMK1ALOX5MGLLCA1CA2
SCHEMBL283191 0.97 LIMK1 (0.46) LIMK1ALOX5MGLLCA1CA2
SCHEMBL30152022 0.97 LIMK1 (0.46) LIMK1ALOX5MGLLCA1CA2
SCHEMBL21125713 0.91 ALOX5 (0.43) LIMK1ALOX5MGLLCA1CA2
SCHEMBL23623782 0.87 LIMK1 (0.41) LIMK1ALOX5MGLLCA1CA2
SCHEMBL21622597 0.87 MGLL (0.37) LIMK1ALOX5MGLLCA1CA2
SCHEMBL29307810 0.86 CA1 (0.58) LIMK1ALOX5MGLLCA1CA2
SCHEMBL22151553 0.85 LIMK1 (0.54) LIMK1ALOX5CA1CA2PDCD1
SCHEMBL18435734 0.85 LIMK1 (0.54) LIMK1ALOX5CA1CA2PDCD1
SCHEMBL29307812 0.84 MGLL (0.55) LIMK1ALOX5MGLLCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12635409-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-05-19 US disclosed
EP-4167707-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2025-12-10 EP disclosed
US-20240298534-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-09-05 US disclosed
US-11957047-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-04-09 US disclosed
US-20230130110-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 US disclosed
US-20230130110-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 US disclosed
EP-4167707-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-04-19 EP disclosed
EP-3591728-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2022-12-14 EP disclosed
US-11456423-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-09-27 US disclosed
US-20210257554-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-08-19 US disclosed
US-11024811-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-06-01 US disclosed
EP-2966706-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2019-09-04 EP disclosed
US-20190259957-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-08-22 US disclosed
US-10297762-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-05-21 US disclosed
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-01-28 US disclosed
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-01-28 US disclosed
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-01-28 US disclosed
EP-2966706-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2016-01-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OR10J3 LIMK1 115/4885ALOX5 336/4885MGLL 519/4885
US-20190259957-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, PIEZO1, L1CAM LIMK1 199/4885ALOX5 3441/4885MGLL 1527/4885
US-11456423-B2 Organic electroluminescent materials and devices SOD1, PIEZO1, L1CAM LIMK1 199/4885ALOX5 3441/4885MGLL 1527/4885
US-12635409-B2 Organic electroluminescent materials and devices NSUN2, CTNND1, NSD1 LIMK1 1686/4885ALOX5 1852/4885MGLL 1567/4885
US-20210257554-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, PIEZO1, L1CAM LIMK1 199/4885ALOX5 3441/4885MGLL 1527/4885
US-11024811-B2 Organic electroluminescent materials and devices SOD1, PIEZO1, L1CAM LIMK1 199/4885ALOX5 3441/4885MGLL 1527/4885
US-11957047-B2 Organic electroluminescent materials and devices SOD1, PIEZO1, L1CAM LIMK1 199/4885ALOX5 3441/4885MGLL 1527/4885
US-20230130110-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, PIEZO1, L1CAM LIMK1 199/4885ALOX5 3441/4885MGLL 1527/4885
US-10297762-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OR10J3 LIMK1 115/4885ALOX5 336/4885MGLL 519/4885
US-20240298534-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, PIEZO1, L1CAM LIMK1 199/4885ALOX5 3441/4885MGLL 1527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.