SCHEMBL1741702

SCHEMBL1741702

CC[CH]Sc1ccc(Br)cc1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.39
MAOB P27338 4/20 0.38
SMN1; SMN2 Q16637 3/20 0.37
CYP2A6 P11509 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ALDH1A1 P00352 1/20 0.35
LMNA P02545 2/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
HAO1 Q9UJM8 1/20 0.33
HSP90AA1 P07900 1/20 0.33
KCNH2 Q12809 1/20 0.33
DHFR P00374 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
SDCBP O00560 1/20 0.31
SDC2 P34741 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1740014 0.79 TDP1 (0.38) MEN1KMT2AALDH1A1LMNAHAO1
SCHEMBL1739829 0.77 MEN1 (0.38) MAOAMAOBCYP2A6MEN1KMT2A
SCHEMBL3071242 0.76 ALDH1A1 (0.40) MAOAMAOBSMN1; SMN2MEN1KMT2A
SCHEMBL1739803 0.74 CA1 (0.46) SMN1; SMN2CYP2A6MEN1KMT2AALDH1A1
SCHEMBL1739837 0.73 CYP2A6 (0.42) MAOAMAOBSMN1; SMN2CYP2A6MEN1
SCHEMBL7810644 0.73 NOS1 (0.50) SMN1; SMN2MEN1KMT2AALDH1A1LMNA
SCHEMBL2095878 0.69 MAOA (0.54) MAOAMAOBSMN1; SMN2CYP2A6MEN1
SCHEMBL5849990 0.69 CYP2A6 (0.42) MAOAMAOBSMN1; SMN2CYP2A6ALDH1A1
SCHEMBL4123832 0.68 MAOA (0.64) MAOAMAOBSMN1; SMN2CYP2A6MEN1
SCHEMBL3411276 0.68 MAOA (0.64) MAOAMAOBSMN1; SMN2CYP2A6MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8669025-B2 Polymerizable composition, cured film, color filter, method of producing color filter and solid-state image sensor FUJIFILM CORPORATION (JP) 2014-03-11 US disclosed
EP-2390272-A1 Polymerizable composition, cured film, color filter, method of producing color filter and solid-state image sensor FUJIFILM Corporation (JP) 2011-11-30 EP disclosed
US-20110255570-A1 ADAPTIVE FREQUENCY HOPPING IN TIME-SLOTTED BASED WIRELESS NETWORK HITACHI, LTD. (JP) 2011-10-20 US disclosed