Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 4/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | TGM2 | P21980 | 3/20 | 0.34 |
| ▸ | F13A1 | P00488 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TGM1 | P22735 | 1/20 | 0.34 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.32 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5850325 | 0.86 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL1195844 | 0.78 | NR1H2 (0.41) | MAOAMAOBLMNAMAPK1 | |
| Water SCHEMBL5850285 | 0.76 | — | — | |
| SCHEMBL28765835 | 0.74 | CYP3A4 (0.50) | MAOAMAOBSMN1; SMN2ALDH1A1ALOX15 | |
| SCHEMBL28765831 | 0.74 | NR1H2 (0.50) | LMNAALDH1A1ALOX15CYP2C19 | |
| SCHEMBL29254132 | 0.74 | CYP2A6 (0.42) | CYP2A6MAOAMAOBLMNASMN1; SMN2 | |
| SCHEMBL1739837 | 0.74 | CYP2A6 (0.42) | CYP2A6MAOAMAOBLMNASMN1; SMN2 | |
| SCHEMBL3392085 | 0.74 | LMNA (0.42) | CYP2A6MAOAMAOBLMNAALDH1A1 | |
| SCHEMBL5835289 | 0.74 | ACHE (0.42) | CYP2A6TGM2LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL17629194 | 0.74 | TGM2 (0.34) | MAOAMAOBTGM2SMN1; SMN2FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7148383-B2 | Low loss high refractive index vinyl sulfide compounds and method of making same | CORNING INCORPORATED (US) | 2006-12-12 | — | — | US | disclosed |
| US-20050240060-A1 | Low loss high refractive index vinyl sulfide compounds and method of making same | LESLIE THOMAS M | 2005-10-27 | — | — | US | disclosed |
| US-6933412-B2 | Low loss high refractive index vinyl sulfide compounds and method of making same | CORNING INCORPORATED (US) | 2005-08-23 | — | — | US | disclosed |
| US-20040044251-A1 | Low loss high refractive index vinyl sulfide compounds and method of making same | CORNING INCORPORATED | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050240060-A1 | Low loss high refractive index vinyl sulfide compounds and method of making same | CRY2, SOS2, CRYZ | CYP2A6 417/4885MAOA 4524/4885MAOB 4428/4885 |
| US-20040044251-A1 | Low loss high refractive index vinyl sulfide compounds and method of making same | SOS2, CRY2, PER2 | CYP2A6 476/4885MAOA 4354/4885MAOB 4140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.