Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17433483 | 0.87 | HTR7 (0.46) | MAPK1ALOX15LMNAMAPTTSHR | |
| SCHEMBL17422793 | 0.86 | HTR7 (0.54) | MAPK1ALOX15ALDH1A1MAPTHTR7 | |
| SCHEMBL1855669 | 0.76 | MAPK1 (0.51) | MAPK1ALOX15ALDH1A1LMNAMAPT | |
| SCHEMBL17422764 | 0.76 | MCL1 (0.41) | MAPTKMT2AHTT | |
| SCHEMBL15837038 | 0.75 | ALOX15 (0.54) | MAPK1ALOX15ALDH1A1LMNAMAPT | |
| SCHEMBL17422738 | 0.74 | MAPK1 (0.44) | MAPK1ALOX15ALDH1A1LMNAMAPT | |
| SCHEMBL16416706 | 0.74 | HTR7 (0.67) | MAPK1ALOX15HTR7 | |
| SCHEMBL15441474 | 0.74 | TRPV4 (0.48) | MAPK1ALOX15ALDH1A1MAPTKMT2A | |
| SCHEMBL19252189 | 0.72 | MCL1 (0.39) | MAPTKMT2A | |
| SCHEMBL30641089 | 0.72 | MAPK1 (0.49) | MAPK1ALOX15ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170216252-A1 | ANTI-BACTERIAL PYRUVATE KINASE MODULATOR COMPOUNDS, COMPOSITIONS, USES AND METHODS | SIMON FRASER UNIVERSITY (CA) | 2017-08-03 | — | — | US | disclosed |
| WO-2016004513-A1 | ANTI-BACTERIAL PYRUVATE KINASE MODULATOR COMPOUNDS, COMPOSITIONS, USES AND METHODS | SIMON FRASER UNIVERSITY (CA) | 2016-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170216252-A1 | ANTI-BACTERIAL PYRUVATE KINASE MODULATOR COMPOUNDS, COMPOSITIONS, USES AND METHODS | PDK1, PDK3, PDK2 | MAPK1 256/4885ALOX15 3483/4885ALDH1A1 2424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.