SCHEMBL17428

SCHEMBL17428

COC(=O)C(=C(c1ccccc1)C(C)C)C(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.47
KMT2A Q03164 5/20 0.41
SMN1; SMN2 Q16637 4/20 0.41
MEN1 O00255 3/20 0.41
HPGD P15428 2/20 0.41
KDM4E B2RXH2 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
MAPT P10636 2/20 0.41
CES1 P23141 2/20 0.41
CYP3A4 P08684 1/20 0.41
ALOX15 P16050 1/20 0.41
MAPK1 P28482 1/20 0.41
GAA P10253 2/20 0.41
NPSR1 Q6W5P4 3/20 0.40
HTT P42858 2/20 0.40
RAB9A P51151 2/20 0.40
ALDH1A1 P00352 1/20 0.40
ELANE P08246 1/20 0.40
PTGS2 P35354 2/20 0.40
PTGS1 P23219 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31119064 1.00 TSHR (0.47) TSHRKMT2ASMN1; SMN2MEN1HPGD
SCHEMBL27941236 0.84 TSHR (0.48) TSHRKMT2ASMN1; SMN2MEN1HPGD
SCHEMBL15513 0.81 ALDH1A1 (0.51) TSHRKMT2ASMN1; SMN2MEN1MAPT
SCHEMBL1173261 0.81 PGR (0.43) TSHRKMT2ASMN1; SMN2MEN1HPGD
SCHEMBL4279863 0.76 TSHR (0.48) TSHRKMT2ASMN1; SMN2MEN1HPGD
SCHEMBL28352415 0.73 TSHR (0.50) TSHRKMT2ASMN1; SMN2HPGDKDM4E
SCHEMBL6472265 0.73 CES1 (0.45) TSHRKMT2ASMN1; SMN2MEN1HPGD
SCHEMBL28754200 0.72 TSHR (0.44) TSHRKMT2ASMN1; SMN2MEN1KDM4E
SCHEMBL15673297 0.71 SMN1; SMN2 (0.44) TSHRKMT2ASMN1; SMN2MEN1HPGD
SCHEMBL10011723 0.71 ALDH1A1 (0.41) TSHRKMT2ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2975 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119015394-A Sulfur-containing compound preparation, and preparation method and application thereof 上海优斐斯生物科技有限公司 2024-11-26 CN claimed
US-20240374492-A1 A SUNSCREEN COMPOSITION COMPRISING AVOBENZONE AND A METHOD FOR PHOTOSTABILIZATION ISP INVESTMENTS LLC (US) 2024-11-14 US claimed
US-20240173235-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS MOMENTIVE PERFORMANCE MATERIALS INC. 2024-05-30 US claimed
EP-4322915-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS Momentive Performance Materials Inc. (US) 2024-02-21 EP claimed
CN-117425467-A Personal care compositions comprising silicone based 迈图高新材料公司 2024-01-19 CN claimed
WO-2023009315-A1 A SUNSCREEN COMPOSITION COMPRISING AVOBENZONE AND A METHOD FOR PHOTOSTABILIZATION ISP INVESTMENTS LLC (US) 2023-02-02 WO claimed
WO-2022221354-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2022-10-20 WO claimed
CN-114828816-A Composition for conditioning keratin fibers 莱雅公司 2022-07-29 CN claimed
CN-112914020-A Aqueous clear oil-in-water emulsions containing emulsified carotenoids 巴斯夫欧洲公司 2021-06-08 CN claimed
EP-2874507-B1 AQUEOUS TRANSPARENT OIL-IN-WATER EMULSION COMPRISING AN EMULSIFIED CAROTENOID BASF SE (DE) 2020-12-30 EP claimed
EP-1107728-B1 COSMETIC COMPOSITIONS FOR SOLAR PROTECTION AND USES OREAL (FR) 2004-04-28 EP claimed
EP-1002523-B1 Cosmetic sunscreening compositions OREAL (FR) 2004-03-03 EP claimed
US-20040028642-A1 Cosmetic composition comprising an extract of emblica officinalis and methods of using same L'OREAL S.A. (FR) 2004-02-12 US claimed
CN-1130193-C Sunlight protection cosmetics compositions and use thereof OREAL (FR) 2003-12-10 CN claimed
US-20020131939-A1 Hair protection compositions ROCHE VITAMINS INC. 2002-09-19 US claimed
US-6409999-B2 Synergistically UV-photoprotecting benzotriazole-substituted silicon/cinnamic acid compositions SOCIETE L'OREAL (FR) 2002-06-25 US claimed
US-20010041167-A1 Synergistically UV-photoprotecting benzotriazole-substituted silicon/cinnamic acid compositions SOCIETE L'OREAL S.A. (FR) 2001-11-15 US claimed
CN-1310607-A Cosmetic compositions for solar protection and uses OREAL (FR) 2001-08-29 CN claimed
US-6143282-A TOPICAL APPLYING SOCIETE L'OREAL S.A. (FR) 2000-11-07 US claimed
CN-1250649-A Sunlight protection cosmetics compositions and use thereof OREAL (FR) 2000-04-19 CN claimed