Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL755236 | 0.80 | TSHR (0.41) | TSHRSRCKMT2AGAAALDH1A1 | |
| SCHEMBL4884737 | 0.80 | KCNK3 (0.43) | KMT2AGAAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL27941236 | 0.78 | TSHR (0.48) | TSHRSRCKMT2AGAAALDH1A1 | |
| SCHEMBL17428 | 0.76 | TSHR (0.47) | TSHRSRCKMT2AGAAALDH1A1 | |
| SCHEMBL31119064 | 0.76 | TSHR (0.47) | TSHRSRCKMT2AGAAALDH1A1 | |
| SCHEMBL15673297 | 0.76 | SMN1; SMN2 (0.44) | TSHRKMT2AGAAALDH1A1NPSR1 | |
| SCHEMBL6576791 | 0.76 | TSHR (0.56) | TSHRSRCKMT2AALDH1A1RAB9A | |
| SCHEMBL6472265 | 0.75 | CES1 (0.45) | TSHRKMT2AGAAALDH1A1NPSR1 | |
| SCHEMBL1173261 | 0.75 | PGR (0.43) | TSHRKMT2AGAAALDH1A1NPSR1 | |
| SCHEMBL1576740 | 0.75 | TSHR (0.54) | TSHRSRCKMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154510-B1 | COMPOSITION FOR PROTECTING KERATIN MATERIALS FROM SUN | OREAL (FR) | 2022-01-19 | — | — | EP | claimed |
| EP-1866033-B1 | SUNSCREEN AEROSOL SPRAY | ENSIGN LABORATORIES PTY LTD (AU) | 2017-04-19 | — | — | EP | claimed |
| US-20190038538-A1 | RNA COMPLEXES THAT INHIBIT MELANIN PRODUCTION | OLIX PHARMACEUTICALS, INC. (KR) | 2019-02-07 | — | — | US | disclosed |
| US-10064801-B2 | RNA complexes that inhibit melanin production | OLIX PHARMACEUTICALS, INC. (KR) | 2018-09-04 | — | — | US | disclosed |
| WO-2017017523-A1 | RNA COMPLEXES THAT INHIBIT MELANIN PRODUCTION | OLIX PHARMACEUTICALS, INC. (KR) | 2017-02-02 | — | — | WO | disclosed |
| US-20170027837-A1 | RNA COMPLEXES THAT INHIBIT MELANIN PRODUCTION | OLIX PHARMACEUTICALS, INC. (KR) | 2017-02-02 | — | — | US | disclosed |
| US-9012418-B2 | Topical administration of at least one double-stranded RNA oligonucleotide (dsRNA) | L'OREAL (FR) | 2015-04-21 | — | — | US | disclosed |
| EP-1309532-B1 | METHOD FOR OBTAINING COCOA BEAN POLYPHENOL EXTRACTS, RESULTING EXTRACTS AND USES THEREOF | BARRY CALLEBAUT AG (CH) | 2013-02-27 | — | — | EP | disclosed |
| US-20090117063-A1 | Topical administration of at least one double-stranded RNA oligonucleotide (dsRNA) | DURANTON ALBERT | 2009-05-07 | — | — | US | disclosed |
| US-7368144-B2 | Method for obtaining cocoa bean polyphenol extracts, resulting extracts and uses thereof | BARRY CALLEBAUT FRANCE (FR) | 2008-05-06 | — | — | US | disclosed |
| US-20070258920-A1 | Process for obtaining polyphenol extracts from cocoa beans, the resulting extracts and uses thereof | BARRY CALLEBAUT AG (CH) | 2007-11-08 | — | — | US | disclosed |
| EP-0998445-B1 | COMPOSITIONS BASED ON RESVERATROL | CAUDALIE (FR) | 2003-10-01 | — | — | EP | disclosed |
| US-6572882-B1 | Having in particular a high stability as regards air and light; esterification | CAUDALIE (FR) | 2003-06-03 | — | — | US | disclosed |
| EP-1309532-A1 | METHOD FOR OBTAINING COCOA BEAN POLYPHENOL EXTRACTS, RESULTING EXTRACTS AND USES THEREOF | Barry Callebaut AG. (CH) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002014251-A1 | METHOD FOR OBTAINING COCOA BEAN POLYPHENOL EXTRACTS, RESULTING EXTRACTS AND USES THEREOF | BARRY CALLEBAUT AG. (CH) | 2002-02-21 | — | — | WO | disclosed |
| EP-0703954-B1 | POLYPHENOL DERIVATIVE COMPOSITIONS AND PREPARATION THEREOF | BERKEM SA (FR) | 2001-12-19 | — | — | EP | disclosed |
| EP-0998445-A1 | COMPOSITIONS BASED ON RESVERATROL | Caudalie (FR) | 2000-05-10 | — | — | EP | disclosed |
| WO-1999003816-A1 | COMPOSITIONS BASED ON RESVERATROL | CAUDALIE (FR) | 1999-01-28 | — | — | WO | disclosed |
| EP-0703954-A1 | POLYPHENOL DERIVATIVE COMPOSITIONS AND PREPARATION THEREOF | BERKEM (FR) | 1996-04-03 | — | — | EP | disclosed |
| WO-1994029404-A1 | POLYPHENOL DERIVATIVE COMPOSITIONS AND PREPARATION THEREOF | BERKEM (FR) | 1994-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090117063-A1 | Topical administration of at least one double-stranded RNA oligonucleotide (dsRNA) | DCLRE1B, POLRMT, ADAR | TSHR 3322/4885SRC 4099/4885KMT2A 3634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.