Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.45 |
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16697813 | 0.84 | CES1 (0.42) | CES1CES2MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL6472934 | 0.84 | MAPT (0.44) | CES1CES2MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL1173261 | 0.83 | PGR (0.43) | CES1CES2MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL15673297 | 0.81 | SMN1; SMN2 (0.44) | CES1CES2MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL8850427 | 0.80 | MAPT (0.53) | CES1CES2MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL28287732 | 0.78 | GAA (0.42) | CES1CES2MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL38971 | 0.77 | LMNA (0.40) | MAPTSMN1; SMN2NPSR1LMNAMEN1 | |
| SCHEMBL29280181 | 0.77 | ELANE (0.38) | CES1CES2MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL367453 | 0.75 | CES1 (0.54) | CES1CES2MAPTSMN1; SMN2LMNA | |
| SCHEMBL1232452 | 0.75 | CES1 (0.54) | CES1CES2MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005109041-A1 | COMPOSITIONS FOR USE IN THE MANUFACTURE OF LENSES | MEDICAL POLYMERS LIMITED (GB) | 2005-11-17 | — | — | WO | disclosed |