SCHEMBL17430596

SCHEMBL17430596

CN1c2ccccc2C(C)(C)c2cc(Br)ccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 14/20 0.46
KMT2A Q03164 10/20 0.46
MEN1 O00255 9/20 0.46
LMNA P02545 8/20 0.46
ALDH1A1 P00352 6/20 0.46
KDM4E B2RXH2 5/20 0.46
MAPK1 P28482 3/20 0.46
HTT P42858 7/20 0.45
GAA P10253 4/20 0.43
THRB P10828 4/20 0.43
RECQL P46063 4/20 0.43
NPSR1 Q6W5P4 2/20 0.43
MMP14 P50281 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
TDP1 Q9NUW8 2/20 0.43
ALOX12 P18054 1/20 0.43
CYP2D6 P10635 2/20 0.41
CYP1A2 P05177 1/20 0.41
GLA P06280 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31711749 0.91 PGR (0.41) MAPTKMT2AMEN1LMNAALDH1A1
SCHEMBL25622875 0.90 MAPT (0.46) MAPTKMT2AMEN1LMNAALDH1A1
SCHEMBL12723265 0.83 HTT (0.51) MAPTKMT2AMEN1LMNAALDH1A1
SCHEMBL280367 0.83 HTT (0.58) MAPTKMT2AMEN1LMNAALDH1A1
SCHEMBL29438184 0.83 HTT (0.58) MAPTKMT2AMEN1LMNAALDH1A1
SCHEMBL19846097 0.82 MAPT (0.53) MAPTKMT2AMEN1LMNAALDH1A1
SCHEMBL31917 0.82 PGR (0.44) MAPTKMT2AMEN1LMNAALDH1A1
SCHEMBL29061592 0.82 KMT2A (0.44) MAPTKMT2AMEN1LMNAALDH1A1
SCHEMBL30007632 0.82 PGR (0.44) MAPTKMT2AMEN1LMNAALDH1A1
SCHEMBL30592716 0.82 KMT2A (0.44) MAPTKMT2AMEN1LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160013426-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING DEVICE, OPTICAL SENSOR, AND METHOD OF USING PHOTOELECTRIC CONVERSION ELEMENT FUJIFILM CORPORATION (JP) 2016-01-14 US disclosed
US-20160013426-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING DEVICE, OPTICAL SENSOR, AND METHOD OF USING PHOTOELECTRIC CONVERSION ELEMENT FUJIFILM CORPORATION (JP) 2016-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160013426-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING DEVICE, OPTICAL SENSOR, AND METHOD OF USING PHOTOELECTRIC CONVERSION ELEMENT PPOX, PIN4, CRY1 MAPT 1641/4885KMT2A 3448/4885MEN1 618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.