Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11554501 | 0.83 | ALDH1A1 (0.32) | ALDH1A1TSHRKMT2ATDP1 | |
| SCHEMBL2836936 | 0.77 | CALM1 (0.46) | ALDH1A1TSHRLMNATP53KDM4E | |
| SCHEMBL9144956 | 0.76 | CALM1 (0.44) | TSHRLMNATP53KDM4EMAPT | |
| SCHEMBL9143779 | 0.76 | CALM1 (0.44) | TSHRLMNATP53KDM4EMAPT | |
| SCHEMBL68390 | 0.74 | SRD5A2 (0.69) | SRD5A2ALDH1A1TSHRRXRARXRB | |
| Hydrochloric Acid SCHEMBL25188150 | 0.72 | SRD5A2 (0.67) | SRD5A2ALDH1A1TSHRRXRARXRB | |
| Hydrochloric Acid SCHEMBL7133360 | 0.72 | SRD5A2 (0.67) | SRD5A2ALDH1A1TSHRRXRARXRB | |
| SCHEMBL12814968 | 0.71 | MGAM (0.31) | GAA | |
| SCHEMBL23522757 | 0.70 | ALDH1A1 (0.39) | ALDH1A1TSHR | |
| SCHEMBL11104544 | 0.70 | ALDH1A1 (0.87) | SRD5A2ALDH1A1TSHRRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9399077-B2 | Metallocene compounds and labeled molecules comprising the same for in vivo imaging | APTENIA S.R.L. (IT) | 2016-07-26 | — | — | US | disclosed |
| US-20160008495-A1 | Metallocene Compounds and Labeled Molecules Comprising the Same for In Vivo Imaging | APTENIA S.R.L. (IT) | 2016-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160008495-A1 | Metallocene Compounds and Labeled Molecules Comprising the Same for In Vivo Imaging | MEN1, MPI, TFRC | SRD5A2 3636/4885ALDH1A1 3718/4885TSHR 487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.