Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | CLK1 | P49759 | 6/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CLK2 | P49760 | 2/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10951469 | 0.86 | MEN1 (0.49) | HDAC1CLK1DYRK1ADYRK1BPPARA | |
| SCHEMBL30474713 | 0.86 | MEN1 (0.49) | HDAC1CLK1DYRK1ADYRK1BPPARA | |
| SCHEMBL9176841 | 0.83 | CYP4F2 (0.51) | STING1HDAC1CLK1DYRK1ADYRK1B | |
| SCHEMBL2947888 | 0.81 | LMNA (0.60) | STING1CLK1DYRK1ADYRK1BPPARA | |
| SCHEMBL17486405 | 0.81 | CLK1 (0.61) | HDAC1CLK1DYRK1ADYRK1BLMNA | |
| SCHEMBL17433717 | 0.80 | HDAC1 (0.49) | STING1HDAC1CLK1DYRK1ADYRK1B | |
| SCHEMBL15876079 | 0.80 | MEN1 (0.48) | STING1HDAC1CLK1DYRK1ADYRK1B | |
| SCHEMBL9757029 | 0.79 | TBXAS1 (0.56) | HDAC1CLK1DYRK1ADYRK1BLMNA | |
| SCHEMBL14793908 | 0.79 | TSHR (0.41) | HDAC1CLK1DYRK1APPARALMNA | |
| SCHEMBL23466533 | 0.78 | CLK1 (0.43) | STING1CLK1DYRK1ADYRK1BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975023-B1 | GUANIDINOBENZOIC ACID ESTER COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2018-05-30 | — | — | EP | disclosed |
| US-9969709-B2 | Guanidinobenzoic acid ester compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-05-15 | — | — | US | disclosed |
| US-20160031847-A1 | GUANIDINOBENZOIC ACID ESTER COMPOUND | ASTELLAS PHARMA INC. (JP) | 2016-02-04 | — | — | US | disclosed |
| EP-2975023-A1 | GUANIDINOBENZOIC ACID ESTER COMPOUND | Astellas Pharma Inc. (JP) | 2016-01-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160031847-A1 | GUANIDINOBENZOIC ACID ESTER COMPOUND | SERPINB1, REN, SPINT2 | STING1 1262/4885HDAC1 1487/4885CLK1 3495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.