Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.34 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.34 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17211371 | 1.00 | ALDH1A1 (0.39) | ALDH1A1LMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2173884 | 1.00 | ALDH1A1 (0.39) | ALDH1A1LMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL20767261 | 1.00 | ALDH1A1 (0.39) | ALDH1A1LMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4557245 | 0.90 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1SMN1; SMN2ADRB2 | |
| SCHEMBL4557017 | 0.90 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1SMN1; SMN2ADRB2 | |
| SCHEMBL1593611 | 0.90 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1SMN1; SMN2ADRB2 | |
| SCHEMBL259017 | 0.90 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1SMN1; SMN2ADRB2 | |
| SCHEMBL4557180 | 0.90 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1SMN1; SMN2ADRB2 | |
| SCHEMBL4557535 | 0.89 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1SMN1; SMN2ADRB2 | |
| SCHEMBL4556420 | 0.89 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1SMN1; SMN2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11008392-B2 | HANP-Fc-containing molecular conjugate | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-05-18 | — | — | US | disclosed |
| US-10947289-B2 | Glyco-modified atrial natriuretic peptide | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-03-16 | — | — | US | disclosed |
| US-20210040170-A1 | GLYCO-MODIFIED ATRIAL NATRIURETIC PEPTIDE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-02-11 | — | — | US | disclosed |
| US-20190169293-A1 | HANP-FC-CONTAINING MOLECULAR CONJUGATE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2019-06-06 | — | — | US | disclosed |
| US-20160017015-A1 | GLYCO-MODIFIED ATRIAL NATRIURETIC PEPTIDE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10947289-B2 | Glyco-modified atrial natriuretic peptide | NPPA, NPR1, NPR3 | ALDH1A1 2820/4885LMNA 1358/4885KMT2A 3687/4885 |
| US-11008392-B2 | HANP-Fc-containing molecular conjugate | FCGRT, FCGR2A, FCGR3B | ALDH1A1 3861/4885LMNA 3774/4885KMT2A 4323/4885 |
| US-20190169293-A1 | HANP-FC-CONTAINING MOLECULAR CONJUGATE | FCGRT, FCGR2A, FCGR3B | ALDH1A1 3861/4885LMNA 3774/4885KMT2A 4323/4885 |
| US-20210040170-A1 | GLYCO-MODIFIED ATRIAL NATRIURETIC PEPTIDE | NPPA, NPR1, NPR3 | ALDH1A1 2820/4885LMNA 1358/4885KMT2A 3687/4885 |
| US-20160017015-A1 | GLYCO-MODIFIED ATRIAL NATRIURETIC PEPTIDE | NPPA, NPR1, NPR3 | ALDH1A1 2820/4885LMNA 1358/4885KMT2A 3687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.